TY - JOUR
T1 - Association of serum Vitamin D with change in weight and total body fat in a German cohort of older adults
AU - Vogt, S.
AU - Zierer, A.
AU - Laxy, M.
AU - Koenig, W.
AU - Linkohr, B.
AU - Linseisen, J.
AU - Peters, A.
AU - Thorand, B.
N1 - Publisher Copyright:
© 2016 Macmillan Publishers Limited All rights reserved.
PY - 2016/1/1
Y1 - 2016/1/1
N2 - We examined the association of baseline serum 25-hydroxyvitamin D (25(OH)D) with change in weight and total body fat in a cohort of community-dwelling older adults from Southern Germany. A total of 735 participants of the population-based KORA-Age Study (2009-2012), aged 65-90 years, were followed for 2.9±0.1 years. Body fat was assessed with bioelectrical impedance analysis. Linear and multinomial logistic models, adjusted for baseline covariables, were used to examine the association of 25(OH)D with percentage weight and body fat change during follow-up. 25(OH)D levels were not associated with overall weight change or body fat loss. Higher 25(OH)D levels were associated with a lower likelihood of having gained >3% of body fat in women but not in men. As we cannot exclude residual confounding by outdoor physical activity and diet, our results are not sufficient to support a causal role of 25(OH)D in the etiology of obesity in Caucasian older adults.
AB - We examined the association of baseline serum 25-hydroxyvitamin D (25(OH)D) with change in weight and total body fat in a cohort of community-dwelling older adults from Southern Germany. A total of 735 participants of the population-based KORA-Age Study (2009-2012), aged 65-90 years, were followed for 2.9±0.1 years. Body fat was assessed with bioelectrical impedance analysis. Linear and multinomial logistic models, adjusted for baseline covariables, were used to examine the association of 25(OH)D with percentage weight and body fat change during follow-up. 25(OH)D levels were not associated with overall weight change or body fat loss. Higher 25(OH)D levels were associated with a lower likelihood of having gained >3% of body fat in women but not in men. As we cannot exclude residual confounding by outdoor physical activity and diet, our results are not sufficient to support a causal role of 25(OH)D in the etiology of obesity in Caucasian older adults.
UR - http://www.scopus.com/inward/record.url?scp=84953634890&partnerID=8YFLogxK
U2 - 10.1038/ejcn.2015.89
DO - 10.1038/ejcn.2015.89
M3 - Article
C2 - 26197877
AN - SCOPUS:84953634890
SN - 0954-3007
VL - 70
SP - 136
EP - 139
JO - European Journal of Clinical Nutrition
JF - European Journal of Clinical Nutrition
IS - 1
ER -
