Association of quadriceps muscle fat with isometric strength measurements in healthy males using chemical shift encoding-based water-fat magnetic resonance imaging

Thomas Baum, Stephanie Inhuber, Michael Dieckmeyer, Christian Cordes, Stefan Ruschke, Elisabeth Klupp, Pia M. Jungmann, Rosanna Farlock, Holger Eggers, Hendrik Kooijman, Ernst J. Rummeny, Ansgar Schwirtz, Jan S. Kirschke, Dimitrios C. Karampinos

Research output: Contribution to journalArticlepeer-review

30 Scopus citations

Abstract

Magnetic resonance-based assessment of quadriceps muscle fat has been proposed as surrogate marker in sarcopenia, osteoarthritis, and neuromuscular disorders. We presently investigated the association of quadriceps muscle fat with isometric strength measurements in healthy males using chemical shift encoding-based water-fat magnetic resonance imaging. Intermuscular adipose tissue fraction and intramuscular proton density fat fraction correlated significantly (P < 0.05) with isometric strength (up to r =-0.83 and-0.87, respectively). Reproducibility of intermuscular adipose tissue fraction and intramuscular proton density fat fraction was 1.5% and 5.7%, respectively.

Original languageEnglish
Pages (from-to)447-451
Number of pages5
JournalJournal of Computer Assisted Tomography
Volume40
Issue number3
DOIs
StatePublished - 2016
Externally publishedYes

Keywords

  • Magnetic resonance imaging
  • Muscle fat
  • Muscle strength
  • Proton density fat fraction

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