Assignment of the porcine tumour necrosis factor alpha and beta genes to the chromosome region 7p11‐q11 by in situ hybridization

S. SOLINAS; U. PAULI; P. KUHNERT; E. PETERHANS; R. FRIES

doi:10.1111/j.1365-2052.1992.tb00140.x

Assignment of the porcine tumour necrosis factor alpha and beta genes to the chromosome region 7p11‐q11 by in situ hybridization

S. SOLINAS, U. PAULI, P. KUHNERT, E. PETERHANS, R. FRIES

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21 Scopus citations

Abstract

Summary. The loci of the porcine tumour necrosis factor genes, alpha (TNFA) and beta (TNFB), have been chromosomally assigned by radioactive in situ hybridization. The genomic probes for TNFA and TNFB yielded signals above 7p11‐q111, a region that has been shown earlier to carry the porcine major histocompatibility locus (SLA). These mapping data along with preliminary molecular studies suggest a genomic organization of the SLA that is similar to that of human and murine major histocompatibility complexes.

Original language	English
Pages (from-to)	267-271
Number of pages	5
Journal	Animal Genetics
Volume	23
Issue number	3
DOIs	https://doi.org/10.1111/j.1365-2052.1992.tb00140.x
State	Published - Jun 1992
Externally published	Yes

Keywords

chromosome 7
gene mapping
major histocompatibility complex
swine
tumour necrosis factor alpha
tumour necrosis factor beta

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10.1111/j.1365-2052.1992.tb00140.x

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title = "Assignment of the porcine tumour necrosis factor alpha and beta genes to the chromosome region 7p11‐q11 by in situ hybridization",

abstract = "Summary. The loci of the porcine tumour necrosis factor genes, alpha (TNFA) and beta (TNFB), have been chromosomally assigned by radioactive in situ hybridization. The genomic probes for TNFA and TNFB yielded signals above 7p11‐q111, a region that has been shown earlier to carry the porcine major histocompatibility locus (SLA). These mapping data along with preliminary molecular studies suggest a genomic organization of the SLA that is similar to that of human and murine major histocompatibility complexes.",

keywords = "chromosome 7, gene mapping, major histocompatibility complex, swine, tumour necrosis factor alpha, tumour necrosis factor beta",

author = "S. SOLINAS and U. PAULI and P. KUHNERT and E. PETERHANS and R. FRIES",

year = "1992",

month = jun,

doi = "10.1111/j.1365-2052.1992.tb00140.x",

language = "English",

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journal = "Animal Genetics",

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T1 - Assignment of the porcine tumour necrosis factor alpha and beta genes to the chromosome region 7p11‐q11 by in situ hybridization

AU - SOLINAS, S.

AU - PAULI, U.

AU - KUHNERT, P.

AU - PETERHANS, E.

AU - FRIES, R.

PY - 1992/6

Y1 - 1992/6

N2 - Summary. The loci of the porcine tumour necrosis factor genes, alpha (TNFA) and beta (TNFB), have been chromosomally assigned by radioactive in situ hybridization. The genomic probes for TNFA and TNFB yielded signals above 7p11‐q111, a region that has been shown earlier to carry the porcine major histocompatibility locus (SLA). These mapping data along with preliminary molecular studies suggest a genomic organization of the SLA that is similar to that of human and murine major histocompatibility complexes.

AB - Summary. The loci of the porcine tumour necrosis factor genes, alpha (TNFA) and beta (TNFB), have been chromosomally assigned by radioactive in situ hybridization. The genomic probes for TNFA and TNFB yielded signals above 7p11‐q111, a region that has been shown earlier to carry the porcine major histocompatibility locus (SLA). These mapping data along with preliminary molecular studies suggest a genomic organization of the SLA that is similar to that of human and murine major histocompatibility complexes.

KW - chromosome 7

KW - gene mapping

KW - major histocompatibility complex

KW - swine

KW - tumour necrosis factor alpha

KW - tumour necrosis factor beta

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U2 - 10.1111/j.1365-2052.1992.tb00140.x

DO - 10.1111/j.1365-2052.1992.tb00140.x

M3 - Article

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AN - SCOPUS:0026478122

SN - 0268-9146

VL - 23

SP - 267

EP - 271

JO - Animal Genetics

JF - Animal Genetics

IS - 3

ER -

Assignment of the porcine tumour necrosis factor alpha and beta genes to the chromosome region 7p11‐q11 by in situ hybridization

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Keywords

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