Assignment of isochores for all completely sequenced vertebrate genomes using a consensus

Thorsten Schmidt, Dmitrij Frishman

Research output: Contribution to journalArticlepeer-review

12 Scopus citations

Abstract

We show that although the currently available isochore mapping methods agree on the isochore classification of about two-thirds of the human DNA, they produce significantly different results with regard to the location of isochore boundaries and isochore length distribution. We present a new consensus isochore assignment method based on majority voting and provide IsoBase, a comprehensive on-line database of isochore maps for all completely sequenced vertebrate genomes.

Original languageEnglish
Article numberR104
JournalGenome Biology
Volume9
Issue number6
DOIs
StatePublished - 30 Jun 2008
Externally publishedYes

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