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Assessing cancer risks of low-dose radiation

  • Leon Mullenders
  • , Mike Atkinson
  • , Herwig Paretzke
  • , Laure Sabatier
  • , Simon Bouffler
  • Leiden University Medical Centre
  • Helmholtz Zentrum München German Research Center for Environmental Health
  • Atomic Research Centre
  • Public Health England

Research output: Contribution to journalReview articlepeer-review

198 Scopus citations

Abstract

Ionizing radiation is considered a non-threshold carcinogen. However, quantifying the risk of the more commonly encountered low and/or protracted radiation exposures remains problematic and subject to uncertainty. Therefore, a major challenge lies in providing a sound mechanistic understanding of low-dose radiation carcinogenesis. This Perspective article considers whether differences exist between the effects mediated by high- and low-dose radiation exposure and how this affects the assessment of low-dose cancer risk.

Original languageEnglish
Pages (from-to)596-604
Number of pages9
JournalNature Reviews Cancer
Volume9
Issue number8
DOIs
StatePublished - Aug 2009

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

  1. SDG 3 - Good Health and Well-being
    SDG 3 Good Health and Well-being

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