Assessing cancer risks of low-dose radiation

Leon Mullenders, Mike Atkinson, Herwig Paretzke, Laure Sabatier, Simon Bouffler

Research output: Contribution to journalReview articlepeer-review

181 Scopus citations


Ionizing radiation is considered a non-threshold carcinogen. However, quantifying the risk of the more commonly encountered low and/or protracted radiation exposures remains problematic and subject to uncertainty. Therefore, a major challenge lies in providing a sound mechanistic understanding of low-dose radiation carcinogenesis. This Perspective article considers whether differences exist between the effects mediated by high- and low-dose radiation exposure and how this affects the assessment of low-dose cancer risk.

Original languageEnglish
Pages (from-to)596-604
Number of pages9
JournalNature Reviews Cancer
Issue number8
StatePublished - Aug 2009
Externally publishedYes


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