Abstract
The symptomatology of allergic diseases may be imitated by non-immunological, so-called 'pseudo-allergic' reactions. Phenocopies of any type of allergic reaction may occur. Pseudo-allergic drug reactions may be caused by the active components as well as by additives. Anaphylactoid pseudo-allergic reactions are of special clinical interest. Their pathomechanism has not been conclusively elucidated yet. Based on clinical and experimental data, we discuss some hypothetical mechanisms of a few compounds, always keeping in mind the possibility of allergic mechanisms not yet identified. For the diagnosis of pseudo-allergic drug reactions we need provocation tests, as skin tests are not possible, and routine in-vitro assays are not available.
| Translated title of the contribution | Adverse drug reactions induced by pseudo-allergic mechanisms |
|---|---|
| Original language | German |
| Pages (from-to) | 130-134 |
| Number of pages | 5 |
| Journal | Wiener Medizinische Wochenschrift |
| Volume | 139 |
| Issue number | 6-7 |
| State | Published - 1989 |
| Externally published | Yes |