TY - JOUR
T1 - Artefact reduction in optoacoustic tomographic imaging by estimating the distribution of acoustic scatterers
AU - Deán-Ben, X. Luís
AU - Ntziachristos, Vasilis
AU - Razansky, Daniel
N1 - Funding Information:
Daniel Razansky acknowledges support from the German Research Foundation (DFG) Research Grant (RA 1848/1) and the ERC Starting Independent Researcher Grant. Vasilis Ntziachristos acknowledges support from the ERC Senior Investigator Award and the Medizin Technik BMBF award for excellence in medical innovation.
PY - 2012/11
Y1 - 2012/11
N2 - The quality of optoacoustic tomographic reconstructions can be severely affected by acoustic reflections or scattering arising at interfaces of highly mismatched organs, such as bones, lungs, or other air-containing cavities. We present a procedure to reduce the associated artefacts based on estimation of the acoustic scatterers distribution within the imaged object. Signals generated by a strong optical absorber are processed and used in a weighted back-projection algorithm. Experimental results in a tissue-mimicking phantom clearly demonstrate improved performance as compared to the case in which no information on the distribution of acoustic scatterers is available.
AB - The quality of optoacoustic tomographic reconstructions can be severely affected by acoustic reflections or scattering arising at interfaces of highly mismatched organs, such as bones, lungs, or other air-containing cavities. We present a procedure to reduce the associated artefacts based on estimation of the acoustic scatterers distribution within the imaged object. Signals generated by a strong optical absorber are processed and used in a weighted back-projection algorithm. Experimental results in a tissue-mimicking phantom clearly demonstrate improved performance as compared to the case in which no information on the distribution of acoustic scatterers is available.
KW - acoustic scattering and reflection
KW - heterogeneous acoustic medium
KW - optoacoustic tomography
UR - http://www.scopus.com/inward/record.url?scp=84870597917&partnerID=8YFLogxK
U2 - 10.1117/1.JBO.17.11.110504
DO - 10.1117/1.JBO.17.11.110504
M3 - Article
C2 - 23096956
AN - SCOPUS:84870597917
SN - 1083-3668
VL - 17
JO - Journal of Biomedical Optics
JF - Journal of Biomedical Optics
IS - 11
M1 - 110504
ER -