Applications of high-speed counter-current chromatography for the separation and isolation of natural products

Norbert Fischer, Bernd Weinreich, Siegfried Nitz, Friedrich Drawert

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20 Scopus citations

Abstract

High-speed counter-current chromatography (HSCCC) with a Ito multi-layer coil separator-extractor was applied to perform efficient separations of natural products and to isolate pure compounds from crude plant extracts. The high performance of the system was demonstrated in the separation and purification of natural antioxidants from rosemary and sage extracts, bitter principles from hops and aromarelevant constituents, such as phthalides, from celery and parsley roots. In addition, the evaluation of a gas chromatographic-compatibel non-aqueous solvent system, suitable for the separation of flavour exracts, is described.

Original languageEnglish
Pages (from-to)193-202
Number of pages10
JournalJournal of Chromatography A
Volume538
Issue number1
DOIs
StatePublished - 18 Jan 1991

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