Application of fuzzy logic in multicomponent analysis by optodes

Markus Wollenweber; Jürgen Polster; Thomas Becker; Schmidt Hanns-Ludwig Schmidt

doi:10.1016/S0956-5663(97)00026-2

Application of fuzzy logic in multicomponent analysis by optodes

Markus Wollenweber, Jürgen Polster, Thomas Becker, Schmidt Hanns-Ludwig Schmidt

Technical University of Munich

Research output: Contribution to journal › Article › peer-review

5 Scopus citations

Abstract

Fuzzy logic can be a useful tool for the determination of substrate concentrations applying optode arrays in combination with flow injection analysis, UV-VIS spectroscopy and kinetics. The transient diffuse reflectance spectra in the visible wavelength region from four optodes were evaluated to carry out the simultaneous determination of artificial mixtures of ampicillin and penicillin. The discrimination of he samples was achieved by changing the composition of the receptor gel and working pH. Different algorithms of pre- processing were applied on the data to reduce the spectral information to a few analytic-specific variables. These variables were used to develop the fuzzy model. After calibration the model was validated by an independent test data set.

Original language	English
Pages (from-to)	917-923
Number of pages	7
Journal	Biosensors and Bioelectronics
Volume	12
Issue number	9-10
DOIs	https://doi.org/10.1016/S0956-5663(97)00026-2
State	Published - Nov 1997

Keywords

Biosensors
Fuzzy logic
Multicomponent analysis
Optodes
Sensor arrays

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10.1016/S0956-5663(97)00026-2

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title = "Application of fuzzy logic in multicomponent analysis by optodes",

abstract = "Fuzzy logic can be a useful tool for the determination of substrate concentrations applying optode arrays in combination with flow injection analysis, UV-VIS spectroscopy and kinetics. The transient diffuse reflectance spectra in the visible wavelength region from four optodes were evaluated to carry out the simultaneous determination of artificial mixtures of ampicillin and penicillin. The discrimination of he samples was achieved by changing the composition of the receptor gel and working pH. Different algorithms of pre- processing were applied on the data to reduce the spectral information to a few analytic-specific variables. These variables were used to develop the fuzzy model. After calibration the model was validated by an independent test data set.",

keywords = "Biosensors, Fuzzy logic, Multicomponent analysis, Optodes, Sensor arrays",

author = "Markus Wollenweber and J{\"u}rgen Polster and Thomas Becker and {Hanns-Ludwig Schmidt}, Schmidt",

note = "Funding Information: This project was partially supported by the Deutsche Forschungsgemeinschaft (SFB 145 Biokonversion). ",

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AU - Polster, Jürgen

AU - Becker, Thomas

AU - Hanns-Ludwig Schmidt, Schmidt

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AB - Fuzzy logic can be a useful tool for the determination of substrate concentrations applying optode arrays in combination with flow injection analysis, UV-VIS spectroscopy and kinetics. The transient diffuse reflectance spectra in the visible wavelength region from four optodes were evaluated to carry out the simultaneous determination of artificial mixtures of ampicillin and penicillin. The discrimination of he samples was achieved by changing the composition of the receptor gel and working pH. Different algorithms of pre- processing were applied on the data to reduce the spectral information to a few analytic-specific variables. These variables were used to develop the fuzzy model. After calibration the model was validated by an independent test data set.

KW - Biosensors

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KW - Multicomponent analysis

KW - Optodes

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Application of fuzzy logic in multicomponent analysis by optodes

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