Application of enhanced sampling Monte Carlo methods for high-resolution protein-protein docking in Rosetta

Keyphrases

• High-resolution 100%
• Monte Carlo Method 100%
• Protein Complex 100%
• Enhanced Sampling 100%
• Protein-protein Docking 100%
• Rosetta 100%
• Hamiltonian Replica Exchange 100%
• Monte Carlo Search 100%
• Temperature Replica Exchange 100%
• Search Strategy 50%
• Efficiency Improvement 50%
• Monte Carlo 50%
• Efficient Search 50%
• Ensemble Methods 50%
• Mechanistic Insight 50%
• Monte Carlo Sampling 50%
• Interaction Geometry 50%
• Structural Insights 50%
• Binding Partners 50%
• Conformational Change 50%
• Near-native 50%
• Ensemble Approach 50%
• Protein Complex Formation 50%
• Monte Carlo Step 50%

Chemistry

• Monte Carlo Method 100%
• Protein Complex 100%
• Statistical Ensemble 66%
• formation 33%

Biochemistry, Genetics and Molecular Biology

• Protein Complexes 100%
• Signal Recognition Particle Receptor 100%
• Conformational Change 33%
• Complex Formation 33%