Apolipoprotein E gene ε2/ε3/ε4 polymorphism and myocardial infarction: Case-control study in a large population sample

Werner Koch; Petra Hoppmann; Albert Schömig; Adnan Kastrati

doi:10.1016/j.ijcard.2007.01.012

Apolipoprotein E gene ε2/ε3/ε4 polymorphism and myocardial infarction: Case-control study in a large population sample

Werner Koch, Petra Hoppmann, Albert Schömig, Adnan Kastrati

Technical University of Munich

Research output: Contribution to journal › Article › peer-review

9 Scopus citations

Abstract

It has not been clearly established yet whether the ε2/ε3/ε4 polymorphism of the gene encoding apolipoprotein E is associated with myocardial infarction. We addressed this issue in a large case-control sample and found no statistically significant relationship between the ε2/ε3/ε4 polymorphism and myocardial infarction. The ε2 allele and ε2ε3 genotype showed trends towards lower risks of myocardial infarction than the ε3ε3 genotype.

Original language	English
Pages (from-to)	116-117
Number of pages	2
Journal	International Journal of Cardiology
Volume	125
Issue number	1
DOIs	https://doi.org/10.1016/j.ijcard.2007.01.012
State	Published - 28 Mar 2008

Keywords

Apolipoprotein E
Atherosclerosis
Genetics
Myocardial infarction

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10.1016/j.ijcard.2007.01.012

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abstract = "It has not been clearly established yet whether the ε2/ε3/ε4 polymorphism of the gene encoding apolipoprotein E is associated with myocardial infarction. We addressed this issue in a large case-control sample and found no statistically significant relationship between the ε2/ε3/ε4 polymorphism and myocardial infarction. The ε2 allele and ε2ε3 genotype showed trends towards lower risks of myocardial infarction than the ε3ε3 genotype.",

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AU - Schömig, Albert

AU - Kastrati, Adnan

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N2 - It has not been clearly established yet whether the ε2/ε3/ε4 polymorphism of the gene encoding apolipoprotein E is associated with myocardial infarction. We addressed this issue in a large case-control sample and found no statistically significant relationship between the ε2/ε3/ε4 polymorphism and myocardial infarction. The ε2 allele and ε2ε3 genotype showed trends towards lower risks of myocardial infarction than the ε3ε3 genotype.

AB - It has not been clearly established yet whether the ε2/ε3/ε4 polymorphism of the gene encoding apolipoprotein E is associated with myocardial infarction. We addressed this issue in a large case-control sample and found no statistically significant relationship between the ε2/ε3/ε4 polymorphism and myocardial infarction. The ε2 allele and ε2ε3 genotype showed trends towards lower risks of myocardial infarction than the ε3ε3 genotype.

KW - Apolipoprotein E

KW - Atherosclerosis

KW - Genetics

KW - Myocardial infarction

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IS - 1

ER -

Apolipoprotein E gene ε2/ε3/ε4 polymorphism and myocardial infarction: Case-control study in a large population sample

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Keywords

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