Antigenotoxic Potential of Some Dietary Non-phenolic Phytochemicals

Ana Clara Aprotosoaie; Vlad Simon Luca; Adriana Trifan; Anca Miron

doi:10.1016/B978-0-444-64181-6.00007-3

Antigenotoxic Potential of Some Dietary Non-phenolic Phytochemicals

Ana Clara Aprotosoaie, Vlad Simon Luca, Adriana Trifan, Anca Miron

“Grigore T. Popa” University of Medicine and Pharmacy Iasi

Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review

27 Scopus citations

Abstract

In recent years there has been a dramatic increase in human exposure to various genotoxic agents, such as ultraviolet light, ionizing radiation, or air, water and food pollutants. Continuous impaired genomic stability is known to cause the mutations that are actively involved in many pathological processes including cancer. A wide array of phytochemicals have been reported to exert genoprotective effects that are mainly related to their antioxidant potential. This chapter discusses the antigenotoxic properties of some nonphenolic phytochemicals, such as organosulfur compounds, terpenoids, and polysaccharides. It does so in terms of study type, mechanisms of activity, structure–activity relationships, and their clinical significance.

Original language	English
Title of host publication	Studies in Natural Products Chemistry
Publisher	Elsevier B.V.
Pages	223-297
Number of pages	75
DOIs	https://doi.org/10.1016/B978-0-444-64181-6.00007-3
State	Published - 1 Jan 2018
Externally published	Yes

Publication series

Name	Studies in Natural Products Chemistry
Volume	60
ISSN (Print)	1572-5995

Keywords

Clinical significance
Genoprotective properties
Organosulfur compounds
Polysaccharides
Terpenoids

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1016/B978-0-444-64181-6.00007-3

Cite this

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title = "Antigenotoxic Potential of Some Dietary Non-phenolic Phytochemicals",

abstract = "In recent years there has been a dramatic increase in human exposure to various genotoxic agents, such as ultraviolet light, ionizing radiation, or air, water and food pollutants. Continuous impaired genomic stability is known to cause the mutations that are actively involved in many pathological processes including cancer. A wide array of phytochemicals have been reported to exert genoprotective effects that are mainly related to their antioxidant potential. This chapter discusses the antigenotoxic properties of some nonphenolic phytochemicals, such as organosulfur compounds, terpenoids, and polysaccharides. It does so in terms of study type, mechanisms of activity, structure–activity relationships, and their clinical significance.",

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AU - Aprotosoaie, Ana Clara

AU - Luca, Vlad Simon

AU - Trifan, Adriana

AU - Miron, Anca

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Y1 - 2018/1/1

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AB - In recent years there has been a dramatic increase in human exposure to various genotoxic agents, such as ultraviolet light, ionizing radiation, or air, water and food pollutants. Continuous impaired genomic stability is known to cause the mutations that are actively involved in many pathological processes including cancer. A wide array of phytochemicals have been reported to exert genoprotective effects that are mainly related to their antioxidant potential. This chapter discusses the antigenotoxic properties of some nonphenolic phytochemicals, such as organosulfur compounds, terpenoids, and polysaccharides. It does so in terms of study type, mechanisms of activity, structure–activity relationships, and their clinical significance.

KW - Clinical significance

KW - Genoprotective properties

KW - Organosulfur compounds

KW - Polysaccharides

KW - Terpenoids

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DO - 10.1016/B978-0-444-64181-6.00007-3

M3 - Chapter

AN - SCOPUS:85057815907

T3 - Studies in Natural Products Chemistry

SP - 223

EP - 297

BT - Studies in Natural Products Chemistry

PB - Elsevier B.V.

ER -

Antigenotoxic Potential of Some Dietary Non-phenolic Phytochemicals

Abstract

Publication series

Keywords

UN SDGs

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