Abstract
According to the WHO [1], approximately 50 million adults and approximately ten million children [2] suffer from epilepsy worldwide; in the USA approximately three million adults and 0.5 million children are affected. In 40% of cases, epilepsy has an underlying central nervous system origin, whereas in 60% there is no identifiable cause. All patients with epilepsy require anticonvulsant therapy with antiepileptic drugs (AEDs) typically as long-term therapy, and approximately one-third require more than one AED; thus, a combination of two or more AEDs and permanent treatment is frequently required. Consequently, these drugs are used in patients with a wide age range from newborn to very old individuals, and treatment cannot be easily paused or changed.
Original language | English |
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Title of host publication | Cutaneous Drug Hypersensitivity |
Subtitle of host publication | Clinical Features, Mechanisms, Diagnosis, and Management |
Publisher | Springer International Publishing |
Pages | 257-266 |
Number of pages | 10 |
ISBN (Electronic) | 9783030827434 |
ISBN (Print) | 9783030827427 |
DOIs | |
State | Published - 9 Jul 2022 |