Anpassung des glucosestoffwechsels bei kälbern nach der geburt

Translated title of the contribution: Adaption of the glucose metabolism in calves after birth

Research output: Contribution to journalReview articlepeer-review


Neonatal calves have to adapt to changes in nutrient supply because energy intake shifts from continuous glucose supply via the placenta to discontinuous colostrum and milk intake with lactose and fat as main energy sources. Besides intake, endogenous glucose production (eGP) is essential in the neonate to assure glucose supply. In the fetus eGP is rare, but endocrine changes before birth, such as an increase of fetal Cortisol, catecholamine and thyroid hormone plasma concentrations, promote maturation of gluconeogenic enzymes. Especially gluconeogensis is very important in newborn to maintain plasma glucose concentrations because hepatic glycogen storage is limited and degrades soon after birth. Postnatal eGP in calves depends on the degree of neonatal maturation and seems to be not stimulated by biologically active substances provided by colostrum feeding. However, colostrum feeding supports glucose absorption, which results in higher plasma glucose concentrations and an elevated glycogen storage in liver. Therefore, a sufficient colostrum supply immediately after birth is important, either for providing immunoglobulins but also for maturation and functioning of the gut to support efficient nutrient absorption and energy supply for growth and development of the neonatal calf.

Translated title of the contributionAdaption of the glucose metabolism in calves after birth
Original languageGerman
Pages (from-to)226-241
Number of pages16
Issue number3
StatePublished - May 2012
Externally publishedYes


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