Animation of aromatic olefins with anilines: A new domino synthesis of quinolines

Matthias Beller, Oliver R. Thiel, Harald Trauthwein, Christian G. Hartung

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A new catalytic animation of aromatic olefins with anilines is presented. In a domino reaction, substituted quinoline derivatives are obtained in the presence of cationic rhodium complexes, such as [Rh(cod)2]BF4, and PPh3. Ethylbenzene is formed as a by-product in this new oxidative reaction. The first transition metal catalyzed anti-Markovnikov hydroamination of styrene with anilines occurs as a side reaction. Mechanistic investigations strongly support the regioselective oxidative amination of styrene as the key reaction step.

Original languageEnglish
Pages (from-to)2513-2522
Number of pages10
JournalChemistry - A European Journal
Issue number14
StatePublished - 17 Jul 2000
Externally publishedYes


  • Anti-Markovnikov aminations
  • Domino reactions
  • Homogeneous catalysis
  • Quinolines
  • Rhodium


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