Analysis of serial MR images of joints

Kelvin K. Leung; Rolf A. Heckemann; Nadeem Saeed; Keith J. Brooks; Jacky B. Buckton; Kumar Changani; David G. Reid; Daniel Rueckert; Joseph V. Hajnal; Mark Holden; Derek L.G. Hill

Analysis of serial MR images of joints

Kelvin K. Leung, Rolf A. Heckemann, Nadeem Saeed, Keith J. Brooks, Jacky B. Buckton, Kumar Changani, David G. Reid, Daniel Rueckert, Joseph V. Hajnal, Mark Holden, Derek L.G. Hill

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › peer-review

4 Scopus citations

Abstract

Medical research and drug discovery rely increasingly on making comparisons between MR images from large numbers of subjects, often with multiple time points for each subject. We show how image registration and visualisation technique can be used for quantitative and qualitative assessment of changes over time in an experimental model of rheumatoid arthritis. We applied the technique to automatically delineate two separate bones (the calcaneus and talus) from the in vivo MR images of an ankle (6 subjects, 6 time points each) by propagating labels from pre-labelled "atlas" MRI scans. As an initial analysis, we calculated their volume and rendered their surfaces in 3D to study the disease progression over time. Finally, we investigated the use of Grid computing by coupling it with image analysis and visualisation algorithms to enable remote invocation, parallel execution, and source data input from heterogeneous distributed image repositories.

Original language	English
Title of host publication	2004 2nd IEEE International Symposium on Biomedical Imaging
Subtitle of host publication	Macro to Nano
Pages	221-224
Number of pages	4
State	Published - 2004
Externally published	Yes
Event	2004 2nd IEEE International Symposium on Biomedical Imaging: Macro to Nano - Arlington, VA, United States Duration: 15 Apr 2004 → 18 Apr 2004

Publication series

Name	2004 2nd IEEE International Symposium on Biomedical Imaging: Macro to Nano
Volume	1

Conference

Conference	2004 2nd IEEE International Symposium on Biomedical Imaging: Macro to Nano
Country/Territory	United States
City	Arlington, VA
Period	15/04/04 → 18/04/04

Cite this

Leung, K. K., Heckemann, R. A., Saeed, N., Brooks, K. J., Buckton, J. B., Changani, K., Reid, D. G., Rueckert, D., Hajnal, J. V., Holden, M., & Hill, D. L. G. (2004). Analysis of serial MR images of joints. In 2004 2nd IEEE International Symposium on Biomedical Imaging: Macro to Nano (pp. 221-224). (2004 2nd IEEE International Symposium on Biomedical Imaging: Macro to Nano; Vol. 1).

@inproceedings{95e1af7f2e274200ae94b868845dd54f,

title = "Analysis of serial MR images of joints",

abstract = "Medical research and drug discovery rely increasingly on making comparisons between MR images from large numbers of subjects, often with multiple time points for each subject. We show how image registration and visualisation technique can be used for quantitative and qualitative assessment of changes over time in an experimental model of rheumatoid arthritis. We applied the technique to automatically delineate two separate bones (the calcaneus and talus) from the in vivo MR images of an ankle (6 subjects, 6 time points each) by propagating labels from pre-labelled {"}atlas{"} MRI scans. As an initial analysis, we calculated their volume and rendered their surfaces in 3D to study the disease progression over time. Finally, we investigated the use of Grid computing by coupling it with image analysis and visualisation algorithms to enable remote invocation, parallel execution, and source data input from heterogeneous distributed image repositories.",

author = "Leung, {Kelvin K.} and Heckemann, {Rolf A.} and Nadeem Saeed and Brooks, {Keith J.} and Buckton, {Jacky B.} and Kumar Changani and Reid, {David G.} and Daniel Rueckert and Hajnal, {Joseph V.} and Mark Holden and Hill, {Derek L.G.}",

year = "2004",

language = "English",

isbn = "0780383885",

series = "2004 2nd IEEE International Symposium on Biomedical Imaging: Macro to Nano",

pages = "221--224",

booktitle = "2004 2nd IEEE International Symposium on Biomedical Imaging",

note = "2004 2nd IEEE International Symposium on Biomedical Imaging: Macro to Nano ; Conference date: 15-04-2004 Through 18-04-2004",

}

Leung, KK, Heckemann, RA, Saeed, N, Brooks, KJ, Buckton, JB, Changani, K, Reid, DG, Rueckert, D, Hajnal, JV, Holden, M & Hill, DLG 2004, Analysis of serial MR images of joints. in 2004 2nd IEEE International Symposium on Biomedical Imaging: Macro to Nano. 2004 2nd IEEE International Symposium on Biomedical Imaging: Macro to Nano, vol. 1, pp. 221-224, 2004 2nd IEEE International Symposium on Biomedical Imaging: Macro to Nano, Arlington, VA, United States, 15/04/04.

Analysis of serial MR images of joints. / Leung, Kelvin K.; Heckemann, Rolf A.; Saeed, Nadeem et al.
2004 2nd IEEE International Symposium on Biomedical Imaging: Macro to Nano. 2004. p. 221-224 (2004 2nd IEEE International Symposium on Biomedical Imaging: Macro to Nano; Vol. 1).

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › peer-review

TY - GEN

T1 - Analysis of serial MR images of joints

AU - Leung, Kelvin K.

AU - Heckemann, Rolf A.

AU - Saeed, Nadeem

AU - Brooks, Keith J.

AU - Buckton, Jacky B.

AU - Changani, Kumar

AU - Reid, David G.

AU - Rueckert, Daniel

AU - Hajnal, Joseph V.

AU - Holden, Mark

AU - Hill, Derek L.G.

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N2 - Medical research and drug discovery rely increasingly on making comparisons between MR images from large numbers of subjects, often with multiple time points for each subject. We show how image registration and visualisation technique can be used for quantitative and qualitative assessment of changes over time in an experimental model of rheumatoid arthritis. We applied the technique to automatically delineate two separate bones (the calcaneus and talus) from the in vivo MR images of an ankle (6 subjects, 6 time points each) by propagating labels from pre-labelled "atlas" MRI scans. As an initial analysis, we calculated their volume and rendered their surfaces in 3D to study the disease progression over time. Finally, we investigated the use of Grid computing by coupling it with image analysis and visualisation algorithms to enable remote invocation, parallel execution, and source data input from heterogeneous distributed image repositories.

AB - Medical research and drug discovery rely increasingly on making comparisons between MR images from large numbers of subjects, often with multiple time points for each subject. We show how image registration and visualisation technique can be used for quantitative and qualitative assessment of changes over time in an experimental model of rheumatoid arthritis. We applied the technique to automatically delineate two separate bones (the calcaneus and talus) from the in vivo MR images of an ankle (6 subjects, 6 time points each) by propagating labels from pre-labelled "atlas" MRI scans. As an initial analysis, we calculated their volume and rendered their surfaces in 3D to study the disease progression over time. Finally, we investigated the use of Grid computing by coupling it with image analysis and visualisation algorithms to enable remote invocation, parallel execution, and source data input from heterogeneous distributed image repositories.

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M3 - Conference contribution

AN - SCOPUS:20244374713

SN - 0780383885

T3 - 2004 2nd IEEE International Symposium on Biomedical Imaging: Macro to Nano

SP - 221

EP - 224

BT - 2004 2nd IEEE International Symposium on Biomedical Imaging

T2 - 2004 2nd IEEE International Symposium on Biomedical Imaging: Macro to Nano

Y2 - 15 April 2004 through 18 April 2004

ER -

Analysis of serial MR images of joints

Abstract

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