An improved procedure for the mild racemization of N-acyl α-amino acids

M. J. Hateley, D. A. Schichl, C. Fischer, M. Beller

Research output: Contribution to journalArticlepeer-review

10 Scopus citations

Abstract

An improved procedure for the mild racemization of N-acyl α-amino acids has been developed, using Pd(PPh3)4 either as the pre-formed complex or by its in situ formation from Pd(OAc)2 or Pd2(dba)3 and triphenylphosphine. The concentration of the palladium complex catalyst required for effective racemization is much lower than for the previously reported rhodium based catalytic system. In addition, the racemization also proceeds more rapidly at this lower catalyst concentration.

Original languageEnglish
Pages (from-to)25-28
Number of pages4
JournalSynlett
Issue number1
DOIs
StatePublished - 2001
Externally publishedYes

Keywords

  • Homogeneous catalysis
  • N-acyl amino acids
  • Palladium
  • Phosphine
  • Racemization

Fingerprint

Dive into the research topics of 'An improved procedure for the mild racemization of N-acyl α-amino acids'. Together they form a unique fingerprint.

Cite this