An efficient and general synthesis of primary amines by ruthenium-catalyzed amination of secondary alcohols with ammonia

Sebastian Imm, Lorenz Neubert, Helfried Neumann, Matthias Beller

Research output: Contribution to journalArticlepeer-review

253 Scopus citations

Abstract

Atom efficiency and selectivity are the key features of the first homogeneously catalyzed amination of secondary alcohols with ammonia to give the corresponding primary amines (see scheme). This novel amination method relies on the commercially available catalyst [Ru3(CO)12]/ cataCXium PCy and does not require any additional source of hydrogen.

Original languageEnglish
Pages (from-to)8126-8129
Number of pages4
JournalAngewandte Chemie International Edition in English
Volume49
Issue number44
DOIs
StatePublished - 25 Oct 2010
Externally publishedYes

Keywords

  • Alcohols
  • Amines
  • Ammonia
  • Homogeneous catalysis
  • Ruthenium

Fingerprint

Dive into the research topics of 'An efficient and general synthesis of primary amines by ruthenium-catalyzed amination of secondary alcohols with ammonia'. Together they form a unique fingerprint.

Cite this