AMP modifications as strategies of bacterial pathogens

Translated title of the contribution: AMP modifications as strategies of bacterial pathogens

Research output: Contribution to journalArticlepeer-review

Abstract

Bacterial pathogens have evolved with enzyme activities that may hijack intracellular signaling of mammalian cells to establish an infection. Of particular interest is a novel posttranslational modification referred to as adenylylation: An adenosine monophosphate group is covalently transferred to a mammalian target protein. Here, I discuss the consequences of adenylylation and its related modifications by Fic enzymes. Also, I comment on potential applications for protein labeling.

Translated title of the contributionAMP modifications as strategies of bacterial pathogens
Original languageEnglish
Pages (from-to)359-361
Number of pages3
JournalBioSpektrum
Volume22
Issue number4
DOIs
StatePublished - Jun 2016

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