Allele-specific change of concentration and functional gene dose for the prediction of steady-state serum concentrations of amitriptyline and nortriptyline in CYP2C19 and CYP2D6 extensive and intermediate metabolizers

Werner Steimer, Konstanze Zöpf, Silvia Von Amelunxen, Herbert Pfeiffer, Julia Bachofer, Johannes Popp, Barbara Messner, Werner Kissling, Stefan Leucht

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Biochemistry, Genetics and Molecular Biology

Neuroscience

Immunology and Microbiology