Abstract
Magnetofection is nucleic acid delivery to cells supported and site-specifically guided by the attractive forces of magnetic fields acting on nucleic acid shuttles (vectors) which are associated with magnetic nanoparticles. Recent progress with the method confirms its general applicability with small and large nucleic acids and viruses. The method's therapeutic application as well as mechanistic studies will be discussed.
Original language | English |
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Pages (from-to) | 501-508 |
Number of pages | 8 |
Journal | Journal of Magnetism and Magnetic Materials |
Volume | 293 |
Issue number | 1 |
DOIs | |
State | Published - May 2005 |
Keywords
- Gene delivery
- Gene therapy
- Magnetic drug targeting
- Magnetofection