Advanced brain tumor imaging in unusual non-enhancing malignant gliomas

Claus Zimmer; Velimir Ivancevic; Randolf Klingebiel; Klaus Peter Wandinger; Frank K.H. Van Landeghem

doi:10.1007/s00062-003-4358-2

Advanced brain tumor imaging in unusual non-enhancing malignant gliomas

Claus Zimmer
, Velimir Ivancevic
, Randolf Klingebiel
, Klaus Peter Wandinger
, Frank K.H. Van Landeghem

Humboldt-Universität zu Berlin
University Hospital Leipzig

Research output: Contribution to journal › Article › peer-review

2 Scopus citations

Abstract

Case Report: The case of an unusual glioblastoma lacking contrast enhancement in computed tomography (CT) and conventional magnetic resonance imaging (MRI) is reported. The low uptake in positron emission tomography (PET) with F18-fluorodeoxyglucose (FDG) suggested a low-grade tumor or a benign inflammatory lesion. Only a significantly increased regional tumor blood volume identified by dynamic MRI (bolus tracking) and a markedly elevated choline level in magnetic resonance spectroscopy (MRS) suggested a highly malignant tumor, which was confirmed histologically (glioblastoma). The role of advanced functional imaging techniques in a typical gliomas lacking contrast enhancement is discussed.

Original language	English
Pages (from-to)	88-91
Number of pages	4
Journal	Klinische Neuroradiologie
Volume	13
Issue number	2
DOIs	https://doi.org/10.1007/s00062-003-4358-2
State	Published - Jun 2003
Externally published	Yes

Keywords

Brain tumor
CT
Malignant gliomas
MRI
MRS
PET

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10.1007/s00062-003-4358-2

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title = "Advanced brain tumor imaging in unusual non-enhancing malignant gliomas",

abstract = "Case Report: The case of an unusual glioblastoma lacking contrast enhancement in computed tomography (CT) and conventional magnetic resonance imaging (MRI) is reported. The low uptake in positron emission tomography (PET) with F18-fluorodeoxyglucose (FDG) suggested a low-grade tumor or a benign inflammatory lesion. Only a significantly increased regional tumor blood volume identified by dynamic MRI (bolus tracking) and a markedly elevated choline level in magnetic resonance spectroscopy (MRS) suggested a highly malignant tumor, which was confirmed histologically (glioblastoma). The role of advanced functional imaging techniques in a typical gliomas lacking contrast enhancement is discussed.",

keywords = "Brain tumor, CT, Malignant gliomas, MRI, MRS, PET",

author = "Claus Zimmer and Velimir Ivancevic and Randolf Klingebiel and Wandinger, \{Klaus Peter\} and \{Van Landeghem\}, \{Frank K.H.\}",

year = "2003",

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doi = "10.1007/s00062-003-4358-2",

language = "English",

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T1 - Advanced brain tumor imaging in unusual non-enhancing malignant gliomas

AU - Zimmer, Claus

AU - Ivancevic, Velimir

AU - Klingebiel, Randolf

AU - Wandinger, Klaus Peter

AU - Van Landeghem, Frank K.H.

PY - 2003/6

Y1 - 2003/6

N2 - Case Report: The case of an unusual glioblastoma lacking contrast enhancement in computed tomography (CT) and conventional magnetic resonance imaging (MRI) is reported. The low uptake in positron emission tomography (PET) with F18-fluorodeoxyglucose (FDG) suggested a low-grade tumor or a benign inflammatory lesion. Only a significantly increased regional tumor blood volume identified by dynamic MRI (bolus tracking) and a markedly elevated choline level in magnetic resonance spectroscopy (MRS) suggested a highly malignant tumor, which was confirmed histologically (glioblastoma). The role of advanced functional imaging techniques in a typical gliomas lacking contrast enhancement is discussed.

AB - Case Report: The case of an unusual glioblastoma lacking contrast enhancement in computed tomography (CT) and conventional magnetic resonance imaging (MRI) is reported. The low uptake in positron emission tomography (PET) with F18-fluorodeoxyglucose (FDG) suggested a low-grade tumor or a benign inflammatory lesion. Only a significantly increased regional tumor blood volume identified by dynamic MRI (bolus tracking) and a markedly elevated choline level in magnetic resonance spectroscopy (MRS) suggested a highly malignant tumor, which was confirmed histologically (glioblastoma). The role of advanced functional imaging techniques in a typical gliomas lacking contrast enhancement is discussed.

KW - Brain tumor

KW - CT

KW - Malignant gliomas

KW - MRI

KW - MRS

KW - PET

UR - https://www.scopus.com/pages/publications/0038354969

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M3 - Article

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EP - 91

JO - Klinische Neuroradiologie

JF - Klinische Neuroradiologie

IS - 2

ER -

Advanced brain tumor imaging in unusual non-enhancing malignant gliomas

Abstract

Keywords

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