Advanced brain tumor imaging in unusual non-enhancing malignant gliomas

Claus Zimmer, Velimir Ivancevic, Randolf Klingebiel, Klaus Peter Wandinger, Frank K.H. Van Landeghem

Research output: Contribution to journalArticlepeer-review

2 Scopus citations


Case Report: The case of an unusual glioblastoma lacking contrast enhancement in computed tomography (CT) and conventional magnetic resonance imaging (MRI) is reported. The low uptake in positron emission tomography (PET) with F18-fluorodeoxyglucose (FDG) suggested a low-grade tumor or a benign inflammatory lesion. Only a significantly increased regional tumor blood volume identified by dynamic MRI (bolus tracking) and a markedly elevated choline level in magnetic resonance spectroscopy (MRS) suggested a highly malignant tumor, which was confirmed histologically (glioblastoma). The role of advanced functional imaging techniques in a typical gliomas lacking contrast enhancement is discussed.

Original languageEnglish
Pages (from-to)88-91
Number of pages4
JournalKlinische Neuroradiologie
Issue number2
StatePublished - Jun 2003
Externally publishedYes


  • Brain tumor
  • CT
  • MRI
  • MRS
  • Malignant gliomas
  • PET


Dive into the research topics of 'Advanced brain tumor imaging in unusual non-enhancing malignant gliomas'. Together they form a unique fingerprint.

Cite this