ADH - induced potassium retention in rats with genetic diabetes insipidus

J. Möhring; A. Schömig; H. Brekner; B. Möhring

doi:10.1016/0024-3205(72)90164-6

ADH - induced potassium retention in rats with genetic diabetes insipidus

J. Möhring
, A. Schömig
, H. Brekner
, B. Möhring

Heidelberg University

Research output: Contribution to journal › Article › peer-review

8 Scopus citations

Abstract

Rats with hereditary hypothalamic diabetes insipidus (D.I.) showed hypokalemia and hypernatremia when compared with normal Wistar rats. After administration of vasopressin tannate to D.I. rats, potassium balance became positive for the subsequent 24 hours, whereas sodium balance was unaffected. In normal control rats ADH had no effect on sodium or potassium balance. Since serum potassium concentration was unchanged 12 hours after ADH injection, it is suggested that the retained potassium is compartmentalized mainly in the intracellular space.

Original language	English
Pages (from-to)	65-72
Number of pages	8
Journal	Life Sciences
Volume	11
Issue number	2 PART 1
DOIs	https://doi.org/10.1016/0024-3205(72)90164-6
State	Published - 15 Jan 1972
Externally published	Yes

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SDG 3 Good Health and Well-being

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10.1016/0024-3205(72)90164-6

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title = "ADH - induced potassium retention in rats with genetic diabetes insipidus",

abstract = "Rats with hereditary hypothalamic diabetes insipidus (D.I.) showed hypokalemia and hypernatremia when compared with normal Wistar rats. After administration of vasopressin tannate to D.I. rats, potassium balance became positive for the subsequent 24 hours, whereas sodium balance was unaffected. In normal control rats ADH had no effect on sodium or potassium balance. Since serum potassium concentration was unchanged 12 hours after ADH injection, it is suggested that the retained potassium is compartmentalized mainly in the intracellular space.",

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AU - Möhring, J.

AU - Schömig, A.

AU - Brekner, H.

AU - Möhring, B.

PY - 1972/1/15

Y1 - 1972/1/15

N2 - Rats with hereditary hypothalamic diabetes insipidus (D.I.) showed hypokalemia and hypernatremia when compared with normal Wistar rats. After administration of vasopressin tannate to D.I. rats, potassium balance became positive for the subsequent 24 hours, whereas sodium balance was unaffected. In normal control rats ADH had no effect on sodium or potassium balance. Since serum potassium concentration was unchanged 12 hours after ADH injection, it is suggested that the retained potassium is compartmentalized mainly in the intracellular space.

AB - Rats with hereditary hypothalamic diabetes insipidus (D.I.) showed hypokalemia and hypernatremia when compared with normal Wistar rats. After administration of vasopressin tannate to D.I. rats, potassium balance became positive for the subsequent 24 hours, whereas sodium balance was unaffected. In normal control rats ADH had no effect on sodium or potassium balance. Since serum potassium concentration was unchanged 12 hours after ADH injection, it is suggested that the retained potassium is compartmentalized mainly in the intracellular space.

UR - https://www.scopus.com/pages/publications/0015506621

U2 - 10.1016/0024-3205(72)90164-6

DO - 10.1016/0024-3205(72)90164-6

M3 - Article

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SP - 65

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JO - Life Sciences

JF - Life Sciences

IS - 2 PART 1

ER -

ADH - induced potassium retention in rats with genetic diabetes insipidus

Abstract

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