Acute valproate poisoning: Pharmacokinetics, alteration in fatty acid metabolism, and changes during therapy

Keyphrases

• Valproic Acid 100%
• Poisoning 100%
• Fatty Acid Metabolism 100%
• Valproate 100%
• Pharmacokinetic Changes 100%
• Hemodialysis 66%
• Ammonia 33%
• Clinical Manifestations 33%
• Central Nervous System 33%
• Clinical Features 33%
• System Features 33%
• Mechanical Ventilation 33%
• Intensive Care 33%
• Multiple Organ Failure 33%
• High Mortality Rate 33%
• Respiratory Failure 33%
• Early Surgery 33%
• Coma 33%
• Clinical Complications 33%
• Cerebral Edema 33%
• Organ Dysfunction 33%
• Patient Mortality 33%
• Long-chain Acylcarnitines 33%
• Medium-chain Acylcarnitines 33%
• Clinical Pharmacology 33%
• Mitochondrial Oxidation 33%
• Hyperammonemia 33%
• ICU Mortality 33%
• Respiratory Depression 33%
• Hemorrhagic Pancreatitis 33%
• Neurologic Conditions 33%

Pharmacology, Toxicology and Pharmaceutical Science

• Toxic Injury 100%
• Sodium Valproate 100%
• Fatty Acid 100%
• Pharmacokinetics 100%
• Hemodialysis 50%
• Hemorrhagic Pancreatitis 25%
• Mortality Rate 25%
• Clinical Feature 25%
• Multiple Organ Failure 25%
• Coma 25%
• Brain Edema 25%
• Acylcarnitine 25%
• Respiration Depression 25%
• Respiratory Failure 25%
• Hyperammonemia 25%