Acute kidney injury after transcatheter aortic valve implantation: Incidence, predictors and impact on mortality

Yacine Elhmidi, Sabine Bleiziffer, Marcus André Deutsch, Markus Krane, Domenico Mazzitelli, Rüdiger Lange, Nicolo Piazza

Research output: Contribution to journalReview articlepeer-review

97 Scopus citations

Abstract

Summary There is a paucity of data describing acute kidney injury (AKI) following transcatheter aortic valve implantation and its impact on mortality remains unknown. We therefore evaluate the incidence, predictors and impact of AKI following transcatheter aortic valve implantation. We searched MEDLINE for studies from 2008 to 2013, evaluating AKI after transcatheter aortic valve implantation. All studies were compared according to the incidence, predictors and impact of AKI following transcatheter aortic valve implantation. AKI was diagnosed according to the Valve Academic Research Consortium definition using the RIFLE criteria. Thirteen studies with more than 1900 patients were included. AKI occurred in 8.3-57% of the patients. The following factors were associated with AKI: blood transfusion; transapical access; preoperative creatinine concentration; peripheral vascular disease; hypertension; and procedural bleeding events. The 30-day mortality rate in patients with AKI ranged from 13.3% to 44.4% and was 2-6-fold higher than in patients without AKI. The amount of contrast agent used was not associated with the occurrence of AKI. AKI is a common complication, with an incidence of 8.3-57% following transcatheter aortic valve implantation. Patients with AKI had higher 30-day and late mortality rates. However, AKI was related to the amount of contrast volume used in only one study.

Original languageEnglish
Pages (from-to)133-139
Number of pages7
JournalArchives of Cardiovascular Diseases
Volume107
Issue number2
DOIs
StatePublished - Feb 2014

Keywords

  • Acute kidney injury
  • RIFLE criteria
  • TAVR

Fingerprint

Dive into the research topics of 'Acute kidney injury after transcatheter aortic valve implantation: Incidence, predictors and impact on mortality'. Together they form a unique fingerprint.

Cite this