Acidification Activates ERp44-A Molecular Litmus Test for Protein Assembly

Linda M. Hendershot; Matthias J. Feige; Johannes Buchner

doi:10.1016/j.molcel.2013.06.008

Acidification Activates ERp44-A Molecular Litmus Test for Protein Assembly

Linda M. Hendershot, Matthias J. Feige, Johannes Buchner

Chair of Biotechnology

St. Jude Children's Research Hospital

Research output: Contribution to journal › Short survey › peer-review

2 Scopus citations

Abstract

In this issue of Molecular Cell, Vavassori etal. (2013) show that a pH-induced conformational change in the quality control protein ERp44 allows retrieval of secretory proteins that contain free thiols via a disulfide linkage from postendoplasmic reticulum compartments to prevent their premature secretion.

Original language	English
Pages (from-to)	779-781
Number of pages	3
Journal	Molecular Cell
Volume	50
Issue number	6
DOIs	https://doi.org/10.1016/j.molcel.2013.06.008
State	Published - 27 Jun 2013

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@article{23ba32f90f9045fcb1cd4a38634413e6,

title = "Acidification Activates ERp44-A Molecular Litmus Test for Protein Assembly",

abstract = "In this issue of Molecular Cell, Vavassori etal. (2013) show that a pH-induced conformational change in the quality control protein ERp44 allows retrieval of secretory proteins that contain free thiols via a disulfide linkage from postendoplasmic reticulum compartments to prevent their premature secretion.",

author = "Hendershot, {Linda M.} and Feige, {Matthias J.} and Johannes Buchner",

year = "2013",

month = jun,

day = "27",

doi = "10.1016/j.molcel.2013.06.008",

language = "English",

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pages = "779--781",

journal = "Molecular Cell",

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T1 - Acidification Activates ERp44-A Molecular Litmus Test for Protein Assembly

AU - Hendershot, Linda M.

AU - Feige, Matthias J.

AU - Buchner, Johannes

PY - 2013/6/27

Y1 - 2013/6/27

N2 - In this issue of Molecular Cell, Vavassori etal. (2013) show that a pH-induced conformational change in the quality control protein ERp44 allows retrieval of secretory proteins that contain free thiols via a disulfide linkage from postendoplasmic reticulum compartments to prevent their premature secretion.

AB - In this issue of Molecular Cell, Vavassori etal. (2013) show that a pH-induced conformational change in the quality control protein ERp44 allows retrieval of secretory proteins that contain free thiols via a disulfide linkage from postendoplasmic reticulum compartments to prevent their premature secretion.

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U2 - 10.1016/j.molcel.2013.06.008

DO - 10.1016/j.molcel.2013.06.008

M3 - Short survey

C2 - 23806332

AN - SCOPUS:84880851624

SN - 1097-2765

VL - 50

SP - 779

EP - 781

JO - Molecular Cell

JF - Molecular Cell

IS - 6

ER -

Acidification Activates ERp44-A Molecular Litmus Test for Protein Assembly

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