Accurate and Efficient Simulation of Microfluidic Networks

Microfluidics is a prospective field which provides technological advances to the life sciences. However, the design process for microfluidic devices is still in its infancy and frequently results in a trial-and-error scheme. In order to overcome this problem, simulation methods provide a powerful solution allowing for deriving a design, validating its functionality, or exploring alternatives without the need of an actual fabricated and costly prototype. To this end, several physical models are available such as Computational Fluid Dynamics (CFD) or the 1-dimensional analysis model. However, while CFD-simulations have high accuracy, they also have high costs with respect to setup and simulation time. On the other hand, the 1D-analysis model is very efficient but lacks in accuracy when it comes to certain phenomena. In this work, we present ideas to combine these two models and, thus, to provide an accurate and efficient simulation approach for microfluidic networks. A case study confirms the general suitability of the proposed approach.