Abstract
The abi2-1 (abscisic acid insensitive) mutant of A. abidopsis thaliana shows abscisic acid (ABA) insensitivity with respect to seed germination and vegetative ABA responses. We identified the ABI2 gene by a combination of positional mapping and homology to ABI1. The ABQ protein shows 80% amino acid sequence identity to ABI1, a protein phosphatase 2C (PP2C) involved in ABA signaling. The mutation that confers the abi2-1 phenotype is equivalent to the mutation previously identified in abi1-1 and the resulting Gly168Asp abi2 protein shows a reduced PP2C activity. Thus, a pair of highly homologous PP2Cs regulate ABA signaling.
Original language | English |
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Pages (from-to) | 185-190 |
Number of pages | 6 |
Journal | FEBS Letters |
Volume | 421 |
Issue number | 3 |
DOIs | |
State | Published - 16 Jan 1998 |
Keywords
- ABI1
- ABI2
- Abscisic acid
- Protein phosphatase 2C
- Signal transduction