Abfall der Serumlipoproteine und Anstieg der Apolipoproteine A-I und A-II nach oraler Zufuhr mehrfach ungesättigter Phospholipide - Beobachtungen zum Einfluß der Ernährung auf die Ergebnisse

Translated title of the contribution: Decrease of serum lipoproteins and increase of apolipoproteins A-I and A-II following oral supply of polyenylphosphatidylcholine. Observations on influence of diet

W. Spann, G. Wolfram, N. Zöllner

Research output: Contribution to journalArticlepeer-review

2 Scopus citations

Abstract

Polyenylphosphatidylcholine was given orally in a dosage of 10 g per day to 10 healthy subjects for 4 weeks. The concentrations of cholesterol, triglycerides, phospholipids, apolipoproteins AI, AII, and B were measured in serum, as were very low density lipoproteins, low density lipoproteins, and high density lipoproteins every 3 h on the day before and after the 4 weeks of application. The diet was controlled 10 days before and during the experiment using the dietary recall method. The evaluation of the diet records showed that 5 subjects had increased and 5 subjects had decreased their fat consumption in exchange for carbohydrates during the experiment. Nevertheless body weight remained constant within ±1 kg. Cholesterol in serum and low density lipoprotein decreased, but the differences were not statistically significant. In spite of dietary changes apolipoprotein AI and AII in high density lipoproteins increased significantly. We conclude that the influence of drugs on serum lipids can only be evaluated in conjunction with reliable control of the diet.

Translated title of the contributionDecrease of serum lipoproteins and increase of apolipoproteins A-I and A-II following oral supply of polyenylphosphatidylcholine. Observations on influence of diet
Original languageGerman
Pages (from-to)590-595
Number of pages6
JournalKlinische Wochenschrift
Volume65
Issue number13
DOIs
StatePublished - Jul 1987

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