TY - GEN
T1 - A Virtual Morris Water Maze to Study Neurodegenarative Disorders
AU - Roth, Daniel
AU - Purps, Christian Felix
AU - Neumann, Wolf Julian
N1 - Publisher Copyright:
© 2020 IEEE.
PY - 2020/11
Y1 - 2020/11
N2 - Navigation is a crucial cognitive skill that allows humans and animals to move from one place to another without getting lost. In neurological patients this skill can be impaired, when neural structures that form the brain networks important for spatial learning and navigation are impaired. Thus, spatial navigation represents an important measure of cognitive health that is impossible to test in a clinical examination, due to lack of space in examination rooms. Consequently, spatial navigation is largely neglected in the clinical assessment of neurological, neurosurgical and psychiatric patients. Virtual reality represents a unique opportunity to develop a systematic assessment of spatial navigation for diagnosis and therapeutic monitoring of millions of patients presenting with cognitive decline in the clinical routine. Therefore, we have adapted a classical spatial navigation paradigm that was developed for animal research, the "Morris Water Maze"as an openly available Virtual Reality (VR) application, that allows objective quantification of navigational skills in humans. This tool may be used in the future to aid the assessment of the human navigation system in health and neurological disease.
AB - Navigation is a crucial cognitive skill that allows humans and animals to move from one place to another without getting lost. In neurological patients this skill can be impaired, when neural structures that form the brain networks important for spatial learning and navigation are impaired. Thus, spatial navigation represents an important measure of cognitive health that is impossible to test in a clinical examination, due to lack of space in examination rooms. Consequently, spatial navigation is largely neglected in the clinical assessment of neurological, neurosurgical and psychiatric patients. Virtual reality represents a unique opportunity to develop a systematic assessment of spatial navigation for diagnosis and therapeutic monitoring of millions of patients presenting with cognitive decline in the clinical routine. Therefore, we have adapted a classical spatial navigation paradigm that was developed for animal research, the "Morris Water Maze"as an openly available Virtual Reality (VR) application, that allows objective quantification of navigational skills in humans. This tool may be used in the future to aid the assessment of the human navigation system in health and neurological disease.
KW - HCI design and evaluation methods
KW - Human computer interaction (HCI)
KW - Human-centered computing
KW - Human-centered computing
KW - Visualization
KW - Visualization design and evaluation methods
UR - http://www.scopus.com/inward/record.url?scp=85099576801&partnerID=8YFLogxK
U2 - 10.1109/ISMAR-Adjunct51615.2020.00048
DO - 10.1109/ISMAR-Adjunct51615.2020.00048
M3 - Conference contribution
AN - SCOPUS:85099576801
T3 - Adjunct Proceedings of the 2020 IEEE International Symposium on Mixed and Augmented Reality, ISMAR-Adjunct 2020
SP - 141
EP - 146
BT - Adjunct Proceedings of the 2020 IEEE International Symposium on Mixed and Augmented Reality, ISMAR-Adjunct 2020
PB - Institute of Electrical and Electronics Engineers Inc.
T2 - 2020 IEEE International Symposium on Mixed and Augmented Reality, ISMAR-Adjunct 2020
Y2 - 9 November 2020 through 13 November 2020
ER -
