A Theranostic Approach for CAR-T Cell Therapy

Wolfgang A. Weber; Zohreh Varasteh; Katja Fritschle; Volker Morath

doi:10.1158/1078-0432.CCR-22-2565

A Theranostic Approach for CAR-T Cell Therapy

Wolfgang A. Weber, Zohreh Varasteh, Katja Fritschle, Volker Morath

Department of Nuclear Medicine

Research output: Contribution to journal › Article › peer-review

3 Scopus citations

Abstract

Fibroblast activation protein (FAP) is frequently expressed in the tumor stroma, whereas expression by normal organs is highly restricted. Despite these promising features, FAP-targeted therapies have shown limited success so far. FAP imaging offers new opportunities to select patients for FAP-targeted therapies and monitor tumor response.

Original language	English
Pages (from-to)	5241-5243
Number of pages	3
Journal	Clinical Cancer Research
Volume	28
Issue number	24
DOIs	https://doi.org/10.1158/1078-0432.CCR-22-2565
State	Published - 15 Dec 2022

Access to Document

10.1158/1078-0432.CCR-22-2565

Cite this

@article{36752054f65f42639a465ae4995771dd,

title = "A Theranostic Approach for CAR-T Cell Therapy",

abstract = "Fibroblast activation protein (FAP) is frequently expressed in the tumor stroma, whereas expression by normal organs is highly restricted. Despite these promising features, FAP-targeted therapies have shown limited success so far. FAP imaging offers new opportunities to select patients for FAP-targeted therapies and monitor tumor response.",

author = "Weber, {Wolfgang A.} and Zohreh Varasteh and Katja Fritschle and Volker Morath",

note = "Publisher Copyright: {\textcopyright}2022 American Association for Cancer Research.",

year = "2022",

month = dec,

day = "15",

doi = "10.1158/1078-0432.CCR-22-2565",

language = "English",

volume = "28",

pages = "5241--5243",

journal = "Clinical Cancer Research",

issn = "1078-0432",

publisher = "American Association for Cancer Research Inc.",

number = "24",

}

TY - JOUR

T1 - A Theranostic Approach for CAR-T Cell Therapy

AU - Weber, Wolfgang A.

AU - Varasteh, Zohreh

AU - Fritschle, Katja

AU - Morath, Volker

PY - 2022/12/15

Y1 - 2022/12/15

N2 - Fibroblast activation protein (FAP) is frequently expressed in the tumor stroma, whereas expression by normal organs is highly restricted. Despite these promising features, FAP-targeted therapies have shown limited success so far. FAP imaging offers new opportunities to select patients for FAP-targeted therapies and monitor tumor response.

AB - Fibroblast activation protein (FAP) is frequently expressed in the tumor stroma, whereas expression by normal organs is highly restricted. Despite these promising features, FAP-targeted therapies have shown limited success so far. FAP imaging offers new opportunities to select patients for FAP-targeted therapies and monitor tumor response.

UR - http://www.scopus.com/inward/record.url?scp=85144586243&partnerID=8YFLogxK

U2 - 10.1158/1078-0432.CCR-22-2565

DO - 10.1158/1078-0432.CCR-22-2565

M3 - Article

C2 - 36250927

AN - SCOPUS:85144586243

SN - 1078-0432

VL - 28

SP - 5241

EP - 5243

JO - Clinical Cancer Research

JF - Clinical Cancer Research

IS - 24

ER -

A Theranostic Approach for CAR-T Cell Therapy

Abstract

Access to Document

Other files and links

Fingerprint

Cite this