A Synaptic Basis for GLP-1 Action in the Brain

Sandrine Lefort; Matthias H. Tschöp; Cristina García-Cáceres

doi:10.1016/j.neuron.2017.10.034

A Synaptic Basis for GLP-1 Action in the Brain

Sandrine Lefort
, Matthias H. Tschöp
, Cristina García-Cáceres

Medicine and Health

Helmholtz Zentrum München
Technical University of Munich

Research output: Contribution to journal › Short survey › peer-review

8 Scopus citations

Abstract

Unraveling the brain control of metabolism may generate opportunities to discover novel precision medicines for obesity and diabetes. In this issue of Neuron, Liu et al. (2017) identify a novel glucagon-like peptide (GLP)-1 receptor-dependent signaling process that exerts anorexigenic action via the regulation of AMPA receptor subunit composition in the hypothalamus. Unraveling the brain control of metabolism may generate opportunities to discover novel precision medicines for obesity and diabetes. In this issue of Neuron, Liu et al. identify a novel glucagon-like peptide (GLP)-1 receptor-dependent signaling process that exerts anorexigenic action via the regulation of AMPA receptor subunit composition in the hypothalamus.

Original language	English
Pages (from-to)	713-715
Number of pages	3
Journal	Neuron
Volume	96
Issue number	4
DOIs	https://doi.org/10.1016/j.neuron.2017.10.034
State	Published - 15 Nov 2017

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10.1016/j.neuron.2017.10.034

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abstract = "Unraveling the brain control of metabolism may generate opportunities to discover novel precision medicines for obesity and diabetes. In this issue of Neuron, Liu et al. (2017) identify a novel glucagon-like peptide (GLP)-1 receptor-dependent signaling process that exerts anorexigenic action via the regulation of AMPA receptor subunit composition in the hypothalamus. Unraveling the brain control of metabolism may generate opportunities to discover novel precision medicines for obesity and diabetes. In this issue of Neuron, Liu et al. identify a novel glucagon-like peptide (GLP)-1 receptor-dependent signaling process that exerts anorexigenic action via the regulation of AMPA receptor subunit composition in the hypothalamus.",

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A Synaptic Basis for GLP-1 Action in the Brain

Abstract

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