TY - GEN
T1 - A statistical method for inverting the born ratio
AU - Hyde, Damon
AU - Miller, Eric
AU - Brooks, Dana
AU - Ntziachristos, Vasilis
PY - 2006
Y1 - 2006
N2 - We examine a statistical solution to the problem of Fluorescence Molecular Tomography (FMT) using the Born ratio. Experimentally verified noise models for the fluorescence and excitation signals are combined to generate a stochastic model for the Born ratio. This model is then utilized within a maximum likelihood (ML) framework to obtain a fixed point iteration about a linear least squares problem. Results for experimental data are shown, including phantoms implanted within a small animal, and in-vivo data using an exogenous probe.
AB - We examine a statistical solution to the problem of Fluorescence Molecular Tomography (FMT) using the Born ratio. Experimentally verified noise models for the fluorescence and excitation signals are combined to generate a stochastic model for the Born ratio. This model is then utilized within a maximum likelihood (ML) framework to obtain a fixed point iteration about a linear least squares problem. Results for experimental data are shown, including phantoms implanted within a small animal, and in-vivo data using an exogenous probe.
UR - https://www.scopus.com/pages/publications/33750961048
U2 - 10.1109/ISBI.2006.1624987
DO - 10.1109/ISBI.2006.1624987
M3 - Conference contribution
AN - SCOPUS:33750961048
SN - 0780395778
SN - 9780780395770
T3 - 2006 3rd IEEE International Symposium on Biomedical Imaging: From Nano to Macro - Proceedings
SP - 598
EP - 601
BT - 2006 3rd IEEE International Symposium on Biomedical Imaging
PB - IEEE Computer Society
T2 - 3rd IEEE International Symposium on Biomedical Imaging: From Nano to Macro, ISBI 2006
Y2 - 6 April 2006 through 9 April 2006
ER -