A Selective and General Cobalt-Catalyzed Hydroaminomethylation of Olefins to Amines

Ji Yang, Fábio G. Delolo, Anke Spannenberg, Ralf Jackstell, Matthias Beller

Research output: Contribution to journalArticlepeer-review

20 Scopus citations

Abstract

A new cobalt catalyst is presented for the domino hydroformylation-reductive amination reaction of olefins. The optimal Co-tert-BuPy-Xantphos catalyst shows good to excellent linear-to-branched (n/iso) regioselectivity for the reactions of aliphatic alkenes with aromatic amines under mild conditions. This system is far more selective than traditional cobalt(I) catalysts and even better than most known rhodium catalysts.

Original languageEnglish
Article numbere202112597
JournalAngewandte Chemie International Edition in English
Volume61
Issue number2
DOIs
StatePublished - 10 Jan 2022
Externally publishedYes

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