A radiomics approach to traumatic brain injury prediction in CT scans

Ezequiel De La Rosa, Diana M. Sima, Thijs Vande Vyvere, Jan S. Kirschke, Bjoern Menze

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

5 Scopus citations

Abstract

Computer Tomography (CT) is the gold standard technique for brain damage evaluation after acute Traumatic Brain Injury (TBI). It allows identification of most lesion types and determines the need of surgical or alternative therapeutic procedures. However, the traditional approach for lesion classification is restricted to visual image inspection. In this work, we characterize and predict TBI lesions by using CT-derived radiomics descriptors. Relevant shape, intensity and texture biomarkers characterizing the different lesions are isolated and a lesion predictive model is built by using Partial Least Squares. On a dataset containing 155 scans (105 train, 50 test) the methodology achieved 89.7% accuracy over the unseen data. When a model was built using only texture features, a 88.2% accuracy was obtained. Our results suggest that selected radiomics descriptors could play a key role in brain injury prediction. Besides, the proposed methodology is close to reproduce radiologists lesion labelling. These results open new possibilities for radiomics-inspired brain lesion detection, segmentation and prediction.

Original languageEnglish
Title of host publicationISBI 2019 - 2019 IEEE International Symposium on Biomedical Imaging
PublisherIEEE Computer Society
Pages732-735
Number of pages4
ISBN (Electronic)9781538636411
DOIs
StatePublished - Apr 2019
Event16th IEEE International Symposium on Biomedical Imaging, ISBI 2019 - Venice, Italy
Duration: 8 Apr 201911 Apr 2019

Publication series

NameProceedings - International Symposium on Biomedical Imaging
Volume2019-April
ISSN (Print)1945-7928
ISSN (Electronic)1945-8452

Conference

Conference16th IEEE International Symposium on Biomedical Imaging, ISBI 2019
Country/TerritoryItaly
CityVenice
Period8/04/1911/04/19

Keywords

  • Ct
  • Radiomics
  • Traumatic brain injury

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