A powerful molecular synergy between mutant Nucleophosmin and Flt3-ITD drives acute myeloid leukemia in mice

A. Mupo; L. Celani; O. Dovey; J. L. Cooper; C. Grove; R. Rad; P. Sportoletti; B. Falini; A. Bradley; G. S. Vassiliou

doi:10.1038/leu.2013.77

A powerful molecular synergy between mutant Nucleophosmin and Flt3-ITD drives acute myeloid leukemia in mice

A. Mupo, L. Celani, O. Dovey, J. L. Cooper, C. Grove, R. Rad, P. Sportoletti, B. Falini, A. Bradley, G. S. Vassiliou

Research output: Contribution to journal › Letter › peer-review

64 Scopus citations

Original language	English
Pages (from-to)	1917-1920
Number of pages	4
Journal	Leukemia
Volume	27
Issue number	9
DOIs	https://doi.org/10.1038/leu.2013.77
State	Published - Sep 2013
Externally published	Yes

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10.1038/leu.2013.77

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@article{10f92f48b4bf424abc16812e22b22262,

title = "A powerful molecular synergy between mutant Nucleophosmin and Flt3-ITD drives acute myeloid leukemia in mice",

author = "A. Mupo and L. Celani and O. Dovey and Cooper, {J. L.} and C. Grove and R. Rad and P. Sportoletti and B. Falini and A. Bradley and Vassiliou, {G. S.}",

note = "Funding Information: We are grateful to Dr Gary Gilliland for his kind donation of the Flt3-ITD mice. We thank James Bussell and the members of the Wellcome Trust Sanger Institute{\textquoteright}s Research Support Facility for help with mouse colony management, controlled procedures and daily welfare checks. We also thank the Haematooncology Diagnostic service and the Pathology Tissue Bank of Cambridge University NHS Trust for their help with sample processing for microscopy. We are grateful to the Wellcome Trust and the Kay Kendall Leukaemia Fund for funding this work and also to Leukaemia Lymphoma Research for funding related work in GV{\textquoteright}s laboratory.",

year = "2013",

month = sep,

doi = "10.1038/leu.2013.77",

language = "English",

volume = "27",

pages = "1917--1920",

journal = "Leukemia",

issn = "0887-6924",

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T1 - A powerful molecular synergy between mutant Nucleophosmin and Flt3-ITD drives acute myeloid leukemia in mice

AU - Mupo, A.

AU - Celani, L.

AU - Dovey, O.

AU - Cooper, J. L.

AU - Grove, C.

AU - Rad, R.

AU - Sportoletti, P.

AU - Falini, B.

AU - Bradley, A.

AU - Vassiliou, G. S.

N1 - Funding Information: We are grateful to Dr Gary Gilliland for his kind donation of the Flt3-ITD mice. We thank James Bussell and the members of the Wellcome Trust Sanger Institute’s Research Support Facility for help with mouse colony management, controlled procedures and daily welfare checks. We also thank the Haematooncology Diagnostic service and the Pathology Tissue Bank of Cambridge University NHS Trust for their help with sample processing for microscopy. We are grateful to the Wellcome Trust and the Kay Kendall Leukaemia Fund for funding this work and also to Leukaemia Lymphoma Research for funding related work in GV’s laboratory.

PY - 2013/9

Y1 - 2013/9

UR - http://www.scopus.com/inward/record.url?scp=84883741078&partnerID=8YFLogxK

U2 - 10.1038/leu.2013.77

DO - 10.1038/leu.2013.77

M3 - Letter

C2 - 23478666

AN - SCOPUS:84883741078

SN - 0887-6924

VL - 27

SP - 1917

EP - 1920

JO - Leukemia

JF - Leukemia

IS - 9

ER -

A powerful molecular synergy between mutant Nucleophosmin and Flt3-ITD drives acute myeloid leukemia in mice

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