A novel Zn-catalyzed hydroamination of propargylamides: A general synthesis of di- and tri-substituted imidazoles

Anahit Pews-Davtyan, Matthias Beller

Research output: Contribution to journalArticlepeer-review

38 Scopus citations

Abstract

Starting from commercially available amines and propargylamides a variety of substituted imidazoles were synthesized via a novel hydroamination-cyclization sequence. The target compounds are obtained in good to excellent yields in the presence of catalytic amounts of zinc triflate.

Original languageEnglish
Pages (from-to)2152-2154
Number of pages3
JournalChemical Communications
Volume47
Issue number7
DOIs
StatePublished - 1 Feb 2011
Externally publishedYes

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