A novel ruthenium-catalyzed amination of primary and secondary alcohols

Annegret Tillack, Dirk Hollmann, Dirk Michalik, Matthias Beller

Research output: Contribution to journalArticlepeer-review

153 Scopus citations

Abstract

An improved method for the N-alkylation of primary amines with primary and secondary alcohols has been developed. Novel, effective catalyst systems, for example, Ru3(CO)12 combined with tri-o-tolylphosphine or n-butyl-di-1-adamantylphosphine, allow for aminations in a good yield under comparatively mild conditions.

Original languageEnglish
Pages (from-to)8881-8885
Number of pages5
JournalTetrahedron Letters
Volume47
Issue number50
DOIs
StatePublished - 11 Dec 2006
Externally publishedYes

Fingerprint

Dive into the research topics of 'A novel ruthenium-catalyzed amination of primary and secondary alcohols'. Together they form a unique fingerprint.

Cite this