A novel enzyme mimic for thiazolium-catalyzed α-ketoacid decarboxylation

N. Bergmann; F. P. Schmidtchen

doi:10.1016/S0040-4039(00)82313-8

A novel enzyme mimic for thiazolium-catalyzed α-ketoacid decarboxylation

N. Bergmann, F. P. Schmidtchen

Natural Sciences

Technical University of Munich

Research output: Contribution to journal › Article › peer-review

16 Scopus citations

Abstract

The covalent combination of the thiazolium heterocycle of thiamine with macrotricyclic quaternary ammonium receptor units yields the enzyme mimics 3a,b, which show enhanced substrate selectivity and catalytic activity in decarboxylations of α-ketoacids compared to simpler salts lacking the receptor substructure.

Original language	English
Pages (from-to)	6235-6238
Number of pages	4
Journal	Tetrahedron Letters
Volume	29
Issue number	48
DOIs	https://doi.org/10.1016/S0040-4039(00)82313-8
State	Published - 1988

Access to Document

10.1016/S0040-4039(00)82313-8

Cite this

@article{7755277c0c744de08e996ddb5f82a6bf,

title = "A novel enzyme mimic for thiazolium-catalyzed α-ketoacid decarboxylation",

abstract = "The covalent combination of the thiazolium heterocycle of thiamine with macrotricyclic quaternary ammonium receptor units yields the enzyme mimics 3a,b, which show enhanced substrate selectivity and catalytic activity in decarboxylations of α-ketoacids compared to simpler salts lacking the receptor substructure.",

author = "N. Bergmann and Schmidtchen, \{F. P.\}",

year = "1988",

doi = "10.1016/S0040-4039(00)82313-8",

language = "English",

volume = "29",

pages = "6235--6238",

journal = "Tetrahedron Letters",

issn = "0040-4039",

publisher = "Elsevier Ltd.",

number = "48",

}

TY - JOUR

T1 - A novel enzyme mimic for thiazolium-catalyzed α-ketoacid decarboxylation

AU - Bergmann, N.

AU - Schmidtchen, F. P.

PY - 1988

Y1 - 1988

N2 - The covalent combination of the thiazolium heterocycle of thiamine with macrotricyclic quaternary ammonium receptor units yields the enzyme mimics 3a,b, which show enhanced substrate selectivity and catalytic activity in decarboxylations of α-ketoacids compared to simpler salts lacking the receptor substructure.

AB - The covalent combination of the thiazolium heterocycle of thiamine with macrotricyclic quaternary ammonium receptor units yields the enzyme mimics 3a,b, which show enhanced substrate selectivity and catalytic activity in decarboxylations of α-ketoacids compared to simpler salts lacking the receptor substructure.

UR - http://www.scopus.com/inward/record.url?scp=0038830097&partnerID=8YFLogxK

U2 - 10.1016/S0040-4039(00)82313-8

DO - 10.1016/S0040-4039(00)82313-8

M3 - Article

AN - SCOPUS:0038830097

SN - 0040-4039

VL - 29

SP - 6235

EP - 6238

JO - Tetrahedron Letters

JF - Tetrahedron Letters

IS - 48

ER -

A novel enzyme mimic for thiazolium-catalyzed α-ketoacid decarboxylation

Abstract

Access to Document

Other files and links

Fingerprint

Cite this