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A new nonviral vector delivered in a fibrin glue matrix for local osteoblast transfection

  • R. Stange
  • , B. Wildemann
  • , A. Stemberger
  • , C. Hacker
  • , C. Plank
  • , N. P. Haas
  • , M. Raschke
  • , G. Schmidmaier

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

Abstract

Non-viral copolymer-protected gene vector (COPROG) and its ability to transfect osteoblasts in vitro were analyzed. Gene vectors were formulated with fibrin glue as a carrier matrix. The dissolved fibrinogen component was mixed with the gene vector suspensions and lyophilized. The results show that the copolymer-protected gene vectors were able to transfer osteoblasts in vitro.

Original languageEnglish
Title of host publicationTransactions - 7th World Biomaterials Congress
Pages1798
Number of pages1
StatePublished - 2004
EventTransactions - 7th World Biomaterials Congress - Sydney, Australia
Duration: 17 May 200421 May 2004

Publication series

NameTransactions - 7th World Biomaterials Congress

Conference

ConferenceTransactions - 7th World Biomaterials Congress
Country/TerritoryAustralia
CitySydney
Period17/05/0421/05/04

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