A model development pipeline for Crohn's disease severity assessment from magnetic resonance images

Peter J. Schüffler, Dwarikanath Mahapatra, Jeroen A.W. Tielbeek, Franciscus M. Vos, Jesica Makanyanga, Doug A. Pendsé, C. Yung Nio, Jaap Stoker, Stuart A. Taylor, Joachim M. Buhmann

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

6 Scopus citations

Abstract

Crohn's Disease affects the intestinal tract of a patient and can have varying severity which influences treatment strategy. The clinical severity score CDEIS (Crohn's Disease Endoscopic Index of severity) ranges from 0 to 44 and is measured by endoscopy. In this paper we investigate the potential of non-invasive magnetic resonance imaging to assess this severity, together with the underlying question which features are most relevant for this estimation task. We propose a new general and modular pipeline that uses machine learning techniques to quantify disease severity from MR images and show its value on Crohn's Disease severity assessment on 30 patients scored by 4 medical experts. With the pipeline, we can obtain a magnetic resonance imaging score which outperforms two existing reference scores MaRIA and AIS.

Original languageEnglish
Title of host publicationAbdominal Imaging
Subtitle of host publicationComputation and Clinical Applications - 5th International Workshop, Held in Conjunction with MICCAI 2013, Proceedings
Pages1-10
Number of pages10
DOIs
StatePublished - 2013
Externally publishedYes
Event5th International Workshop on Abdominal Imaging: Computation and Clinical Applications, Held in Conjunction with 16th International Conference on Medical Image Computing and Computer-Assisted Intervention, MICCAI 2013 - Nagoya, Japan
Duration: 22 Sep 201322 Sep 2013

Publication series

NameLecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics)
Volume8198 LNCS
ISSN (Print)0302-9743
ISSN (Electronic)1611-3349

Conference

Conference5th International Workshop on Abdominal Imaging: Computation and Clinical Applications, Held in Conjunction with 16th International Conference on Medical Image Computing and Computer-Assisted Intervention, MICCAI 2013
Country/TerritoryJapan
CityNagoya
Period22/09/1322/09/13

Keywords

  • AIS
  • CDEIS
  • Crohn's Disease
  • MaRIA
  • abdominal MRI

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