A High-Gradient Magnetic Separator for Highly Viscous Process Liquors in Industrial Biotechnology

Hans Christian Roth; Andreas Prams; Michael Lutz; Jonathan Ritscher; Moritz Raab; Sonja Berensmeier

doi:10.1002/ceat.201500398

A High-Gradient Magnetic Separator for Highly Viscous Process Liquors in Industrial Biotechnology

Hans Christian Roth, Andreas Prams, Michael Lutz, Jonathan Ritscher, Moritz Raab, Sonja Berensmeier

Chair of Bioseparation Engineering

Technical University of Munich

Research output: Contribution to journal › Article › peer-review

15 Scopus citations

Abstract

Following the demand for highly efficient processes in biotechnology, an innovative and cost-effective permanent magnet-based high-gradient magnetic separator with static magnetic filters (SMF) is presented. The laboratory-scale prototype has a high particle capacity and is characterized by an outstanding separation performance. Low-cost magnetic nanoparticles (MNPs, hydrodynamic diameter 100 - 200 nm) were separated from highly viscous sucrose solutions. Losses of MNPs with filtrate remained very low. The in situ implementation of ultrasound technology during MNP-backwashing yielded excellent MNP recovery efficiencies. By applying a non-stick coating onto the SMF surface, the MNP recovery efficiency could be enhanced significantly compared to conventional SMFs.

Original language	English
Pages (from-to)	469-476
Number of pages	8
Journal	Chemical Engineering and Technology
Volume	39
Issue number	3
DOIs	https://doi.org/10.1002/ceat.201500398
State	Published - 1 Mar 2016

Keywords

Filter backwashing
High-gradient magnetic separation
Industrial biotechnology
Non-stick coated filters
Sonication

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10.1002/ceat.201500398

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abstract = "Following the demand for highly efficient processes in biotechnology, an innovative and cost-effective permanent magnet-based high-gradient magnetic separator with static magnetic filters (SMF) is presented. The laboratory-scale prototype has a high particle capacity and is characterized by an outstanding separation performance. Low-cost magnetic nanoparticles (MNPs, hydrodynamic diameter 100 - 200 nm) were separated from highly viscous sucrose solutions. Losses of MNPs with filtrate remained very low. The in situ implementation of ultrasound technology during MNP-backwashing yielded excellent MNP recovery efficiencies. By applying a non-stick coating onto the SMF surface, the MNP recovery efficiency could be enhanced significantly compared to conventional SMFs.",

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AU - Berensmeier, Sonja

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AB - Following the demand for highly efficient processes in biotechnology, an innovative and cost-effective permanent magnet-based high-gradient magnetic separator with static magnetic filters (SMF) is presented. The laboratory-scale prototype has a high particle capacity and is characterized by an outstanding separation performance. Low-cost magnetic nanoparticles (MNPs, hydrodynamic diameter 100 - 200 nm) were separated from highly viscous sucrose solutions. Losses of MNPs with filtrate remained very low. The in situ implementation of ultrasound technology during MNP-backwashing yielded excellent MNP recovery efficiencies. By applying a non-stick coating onto the SMF surface, the MNP recovery efficiency could be enhanced significantly compared to conventional SMFs.

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A High-Gradient Magnetic Separator for Highly Viscous Process Liquors in Industrial Biotechnology

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Keywords

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