A Critical Role for Neocortical Processing of Threat Memory

Tamas Dalmay; Elisabeth Abs; Rogier B. Poorthuis; Jan Hartung; De Lin Pu; Sebastian Onasch; Yave R. Lozano; Jérémy Signoret-Genest; Philip Tovote; Julijana Gjorgjieva; Johannes J. Letzkus

doi:10.1016/j.neuron.2019.09.025

A Critical Role for Neocortical Processing of Threat Memory

Tamas Dalmay, Elisabeth Abs, Rogier B. Poorthuis, Jan Hartung, De Lin Pu, Sebastian Onasch, Yave R. Lozano, Jérémy Signoret-Genest, Philip Tovote, Julijana Gjorgjieva, Johannes J. Letzkus

Associate Professorship of Computational Neuroscience

Research output: Contribution to journal › Article › peer-review

59 Scopus citations

Abstract

Dalmay et al. demonstrate that the neocortex plays a key role in learning and memory, particularly when auditory stimuli are complex and naturalistic. Memory is mediated by plasticity in neurons projecting to the amygdala, the brain's hub for emotions.

Original language	English
Pages (from-to)	1180-1194.e7
Journal	Neuron
Volume	104
Issue number	6
DOIs	https://doi.org/10.1016/j.neuron.2019.09.025
State	Published - 18 Dec 2019

Keywords

associative learning
auditory cortex
behavior
brain-wide circuits
learning-related plasticity
neocortical circuits
neural population coding
stimulus complexity
temporal association cortex
threat conditioning

Access to Document

10.1016/j.neuron.2019.09.025

Cite this

@article{7ef92055d166446296308dce83fbdf29,

title = "A Critical Role for Neocortical Processing of Threat Memory",

abstract = "Dalmay et al. demonstrate that the neocortex plays a key role in learning and memory, particularly when auditory stimuli are complex and naturalistic. Memory is mediated by plasticity in neurons projecting to the amygdala, the brain's hub for emotions.",

keywords = "associative learning, auditory cortex, behavior, brain-wide circuits, learning-related plasticity, neocortical circuits, neural population coding, stimulus complexity, temporal association cortex, threat conditioning",

author = "Tamas Dalmay and Elisabeth Abs and Poorthuis, {Rogier B.} and Jan Hartung and Pu, {De Lin} and Sebastian Onasch and Lozano, {Yave R.} and J{\'e}r{\'e}my Signoret-Genest and Philip Tovote and Julijana Gjorgjieva and Letzkus, {Johannes J.}",

note = "Publisher Copyright: {\textcopyright} 2019 Elsevier Inc.",

year = "2019",

month = dec,

day = "18",

doi = "10.1016/j.neuron.2019.09.025",

language = "English",

volume = "104",

pages = "1180--1194.e7",

journal = "Neuron",

issn = "0896-6273",

publisher = "Cell Press",

number = "6",

}

TY - JOUR

T1 - A Critical Role for Neocortical Processing of Threat Memory

AU - Dalmay, Tamas

AU - Abs, Elisabeth

AU - Poorthuis, Rogier B.

AU - Hartung, Jan

AU - Pu, De Lin

AU - Onasch, Sebastian

AU - Lozano, Yave R.

AU - Signoret-Genest, Jérémy

AU - Tovote, Philip

AU - Gjorgjieva, Julijana

AU - Letzkus, Johannes J.

PY - 2019/12/18

Y1 - 2019/12/18

N2 - Dalmay et al. demonstrate that the neocortex plays a key role in learning and memory, particularly when auditory stimuli are complex and naturalistic. Memory is mediated by plasticity in neurons projecting to the amygdala, the brain's hub for emotions.

AB - Dalmay et al. demonstrate that the neocortex plays a key role in learning and memory, particularly when auditory stimuli are complex and naturalistic. Memory is mediated by plasticity in neurons projecting to the amygdala, the brain's hub for emotions.

KW - associative learning

KW - auditory cortex

KW - behavior

KW - brain-wide circuits

KW - learning-related plasticity

KW - neocortical circuits

KW - neural population coding

KW - stimulus complexity

KW - temporal association cortex

KW - threat conditioning

UR - http://www.scopus.com/inward/record.url?scp=85076252163&partnerID=8YFLogxK

U2 - 10.1016/j.neuron.2019.09.025

DO - 10.1016/j.neuron.2019.09.025

M3 - Article

C2 - 31727549

AN - SCOPUS:85076252163

SN - 0896-6273

VL - 104

SP - 1180-1194.e7

JO - Neuron

JF - Neuron

IS - 6

ER -

A Critical Role for Neocortical Processing of Threat Memory

Abstract

Keywords

Access to Document

Other files and links

Fingerprint

Cite this