A convenient palladium-catalyzed carbonylative synthesis of 4(3H)-quinazolinones from 2-bromoformanilides and organo nitros with Mo(CO) 6 as a multiple promoter

Lin He, Muhammad Sharif, Helfried Neumann, Matthias Beller, Xiao Feng Wu

Research output: Contribution to journalArticlepeer-review

79 Scopus citations

Abstract

A novel and convenient procedure for the synthesis of quinazolinones has been developed. Using 2-bromoformanilides and organo nitros as substrates and Mo(CO)6 as a multiple promoter, the desired products were isolated in moderate to excellent yields in the presence of a palladium catalyst. Here, Mo(CO)6 was not only a CO source, but also a nitro compound reducing reagent and a cyclization promoter. This journal is

Original languageEnglish
Pages (from-to)3763-3767
Number of pages5
JournalGreen Chemistry
Volume16
Issue number8
DOIs
StatePublished - Aug 2014
Externally publishedYes

Fingerprint

Dive into the research topics of 'A convenient palladium-catalyzed carbonylative synthesis of 4(3H)-quinazolinones from 2-bromoformanilides and organo nitros with Mo(CO) 6 as a multiple promoter'. Together they form a unique fingerprint.

Cite this