A convenient and general iron-catalyzed reduction of amides to amines

Shaolin Zhou, Kathrin Junge, Daniele Addis, Shoubhik Das, Matthias Beller

Research output: Contribution to journalArticlepeer-review

248 Scopus citations

Abstract

While the iron is hot: The first general and efficient iron-catalyzed reduction of secondary and tertiary amides into amines using polymethylhydrosiloxane (PMHS) has been developed (see scheme).

Original languageEnglish
Pages (from-to)9507-9510
Number of pages4
JournalAngewandte Chemie International Edition in English
Volume48
Issue number50
DOIs
StatePublished - 7 Dec 2009
Externally publishedYes

Keywords

  • Amides
  • Amines
  • Homogeneous catalysis
  • Iron
  • Reduction

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