A comprehensive genome variation map of melon identifies multiple domestication events and loci influencing agronomic traits

Guangwei Zhao; Qun Lian; Zhonghua Zhang; Qiushi Fu; Yuhua He; Shuangwu Ma; Valentino Ruggieri; Antonio J. Monforte; Pingyong Wang; Irene Julca; Huaisong Wang; Junpu Liu; Yong Xu; Runze Wang; Jiabing Ji; Zhihong Xu; Weihu Kong; Yang Zhong; Jianli Shang; Lara Pereira; Jason Argyris; Jian Zhang; Carlos Mayobre; Marta Pujol; Elad Oren; Diandian Ou; Jiming Wang; Dexi Sun; Shengjie Zhao; Yingchun Zhu; Na Li; Nurit Katzir; Amit Gur; Catherine Dogimont; Hanno Schaefer; Wei Fan; Abdelhafid Bendahmane; Zhangjun Fei; Michel Pitrat; Toni Gabaldón; Tao Lin; Jordi Garcia-Mas; Yongyang Xu; Sanwen Huang

doi:10.1038/s41588-019-0522-8

A comprehensive genome variation map of melon identifies multiple domestication events and loci influencing agronomic traits

Guangwei Zhao, Qun Lian, Zhonghua Zhang, Qiushi Fu, Yuhua He, Shuangwu Ma, Valentino Ruggieri, Antonio J. Monforte, Pingyong Wang, Irene Julca, Huaisong Wang, Junpu Liu, Yong Xu, Runze Wang, Jiabing Ji, Zhihong Xu, Weihu Kong, Yang Zhong, Jianli Shang, Lara PereiraJason Argyris, Jian Zhang, Carlos Mayobre, Marta Pujol, Elad Oren, Diandian Ou, Jiming Wang, Dexi Sun, Shengjie Zhao, Yingchun Zhu, Na Li, Nurit Katzir, Amit Gur, Catherine Dogimont, Hanno Schaefer, Wei Fan, Abdelhafid Bendahmane, Zhangjun Fei, Michel Pitrat, Toni Gabaldón, Tao Lin, Jordi Garcia-Mas, Yongyang Xu, Sanwen Huang

Associate Professorship of Biodiversität der Pflanzen

Research output: Contribution to journal › Article › peer-review

191 Scopus citations

Abstract

Melon is an economically important fruit crop that has been cultivated for thousands of years; however, the genetic basis and history of its domestication still remain largely unknown. Here we report a comprehensive map of the genomic variation in melon derived from the resequencing of 1,175 accessions, which represent the global diversity of the species. Our results suggest that three independent domestication events occurred in melon, two in India and one in Africa. We detected two independent sets of domestication sweeps, resulting in diverse characteristics of the two subspecies melo and agrestis during melon breeding. Genome-wide association studies for 16 agronomic traits identified 208 loci significantly associated with fruit mass, quality and morphological characters. This study sheds light on the domestication history of melon and provides a valuable resource for genomics-assisted breeding of this important crop.

Original language	English
Pages (from-to)	1607-1615
Number of pages	9
Journal	Nature Genetics
Volume	51
Issue number	11
DOIs	https://doi.org/10.1038/s41588-019-0522-8
State	Published - 1 Nov 2019

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Zhao, G., Lian, Q., Zhang, Z., Fu, Q., He, Y., Ma, S., Ruggieri, V., Monforte, A. J., Wang, P., Julca, I., Wang, H., Liu, J., Xu, Y., Wang, R., Ji, J., Xu, Z., Kong, W., Zhong, Y., Shang, J., ... Huang, S. (2019). A comprehensive genome variation map of melon identifies multiple domestication events and loci influencing agronomic traits. Nature Genetics, 51(11), 1607-1615. https://doi.org/10.1038/s41588-019-0522-8

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title = "A comprehensive genome variation map of melon identifies multiple domestication events and loci influencing agronomic traits",

abstract = "Melon is an economically important fruit crop that has been cultivated for thousands of years; however, the genetic basis and history of its domestication still remain largely unknown. Here we report a comprehensive map of the genomic variation in melon derived from the resequencing of 1,175 accessions, which represent the global diversity of the species. Our results suggest that three independent domestication events occurred in melon, two in India and one in Africa. We detected two independent sets of domestication sweeps, resulting in diverse characteristics of the two subspecies melo and agrestis during melon breeding. Genome-wide association studies for 16 agronomic traits identified 208 loci significantly associated with fruit mass, quality and morphological characters. This study sheds light on the domestication history of melon and provides a valuable resource for genomics-assisted breeding of this important crop.",

author = "Guangwei Zhao and Qun Lian and Zhonghua Zhang and Qiushi Fu and Yuhua He and Shuangwu Ma and Valentino Ruggieri and Monforte, {Antonio J.} and Pingyong Wang and Irene Julca and Huaisong Wang and Junpu Liu and Yong Xu and Runze Wang and Jiabing Ji and Zhihong Xu and Weihu Kong and Yang Zhong and Jianli Shang and Lara Pereira and Jason Argyris and Jian Zhang and Carlos Mayobre and Marta Pujol and Elad Oren and Diandian Ou and Jiming Wang and Dexi Sun and Shengjie Zhao and Yingchun Zhu and Na Li and Nurit Katzir and Amit Gur and Catherine Dogimont and Hanno Schaefer and Wei Fan and Abdelhafid Bendahmane and Zhangjun Fei and Michel Pitrat and Toni Gabald{\'o}n and Tao Lin and Jordi Garcia-Mas and Yongyang Xu and Sanwen Huang",

note = "Publisher Copyright: {\textcopyright} 2019, The Author(s), under exclusive licence to Springer Nature America, Inc.",

year = "2019",

month = nov,

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doi = "10.1038/s41588-019-0522-8",

language = "English",

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Zhao, G, Lian, Q, Zhang, Z, Fu, Q, He, Y, Ma, S, Ruggieri, V, Monforte, AJ, Wang, P, Julca, I, Wang, H, Liu, J, Xu, Y, Wang, R, Ji, J, Xu, Z, Kong, W, Zhong, Y, Shang, J, Pereira, L, Argyris, J, Zhang, J, Mayobre, C, Pujol, M, Oren, E, Ou, D, Wang, J, Sun, D, Zhao, S, Zhu, Y, Li, N, Katzir, N, Gur, A, Dogimont, C, Schaefer, H, Fan, W, Bendahmane, A, Fei, Z, Pitrat, M, Gabaldón, T, Lin, T, Garcia-Mas, J, Xu, Y & Huang, S 2019, 'A comprehensive genome variation map of melon identifies multiple domestication events and loci influencing agronomic traits', Nature Genetics, vol. 51, no. 11, pp. 1607-1615. https://doi.org/10.1038/s41588-019-0522-8

TY - JOUR

T1 - A comprehensive genome variation map of melon identifies multiple domestication events and loci influencing agronomic traits

AU - Zhao, Guangwei

AU - Lian, Qun

AU - Zhang, Zhonghua

AU - Fu, Qiushi

AU - He, Yuhua

AU - Ma, Shuangwu

AU - Ruggieri, Valentino

AU - Monforte, Antonio J.

AU - Wang, Pingyong

AU - Julca, Irene

AU - Wang, Huaisong

AU - Liu, Junpu

AU - Xu, Yong

AU - Wang, Runze

AU - Ji, Jiabing

AU - Xu, Zhihong

AU - Kong, Weihu

AU - Zhong, Yang

AU - Shang, Jianli

AU - Pereira, Lara

AU - Argyris, Jason

AU - Zhang, Jian

AU - Mayobre, Carlos

AU - Pujol, Marta

AU - Oren, Elad

AU - Ou, Diandian

AU - Wang, Jiming

AU - Sun, Dexi

AU - Zhao, Shengjie

AU - Zhu, Yingchun

AU - Li, Na

AU - Katzir, Nurit

AU - Gur, Amit

AU - Dogimont, Catherine

AU - Schaefer, Hanno

AU - Fan, Wei

AU - Bendahmane, Abdelhafid

AU - Fei, Zhangjun

AU - Pitrat, Michel

AU - Gabaldón, Toni

AU - Lin, Tao

AU - Garcia-Mas, Jordi

AU - Xu, Yongyang

AU - Huang, Sanwen

PY - 2019/11/1

Y1 - 2019/11/1

N2 - Melon is an economically important fruit crop that has been cultivated for thousands of years; however, the genetic basis and history of its domestication still remain largely unknown. Here we report a comprehensive map of the genomic variation in melon derived from the resequencing of 1,175 accessions, which represent the global diversity of the species. Our results suggest that three independent domestication events occurred in melon, two in India and one in Africa. We detected two independent sets of domestication sweeps, resulting in diverse characteristics of the two subspecies melo and agrestis during melon breeding. Genome-wide association studies for 16 agronomic traits identified 208 loci significantly associated with fruit mass, quality and morphological characters. This study sheds light on the domestication history of melon and provides a valuable resource for genomics-assisted breeding of this important crop.

AB - Melon is an economically important fruit crop that has been cultivated for thousands of years; however, the genetic basis and history of its domestication still remain largely unknown. Here we report a comprehensive map of the genomic variation in melon derived from the resequencing of 1,175 accessions, which represent the global diversity of the species. Our results suggest that three independent domestication events occurred in melon, two in India and one in Africa. We detected two independent sets of domestication sweeps, resulting in diverse characteristics of the two subspecies melo and agrestis during melon breeding. Genome-wide association studies for 16 agronomic traits identified 208 loci significantly associated with fruit mass, quality and morphological characters. This study sheds light on the domestication history of melon and provides a valuable resource for genomics-assisted breeding of this important crop.

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AN - SCOPUS:85074346842

SN - 1061-4036

VL - 51

SP - 1607

EP - 1615

JO - Nature Genetics

JF - Nature Genetics

IS - 11

ER -

A comprehensive genome variation map of melon identifies multiple domestication events and loci influencing agronomic traits

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