A case of multimodality multiparametric ¹¹C-choline PET/MR for biopsy targeting in prior biopsy-negative primary prostate cancer

We introduce the case of a 70-years-old man with an elevated level of prostate-specific antigen and prior negative biopsy. For targeting rebiopsy, the patient underwent ¹¹C-choline PET/CT and subsequent PET/MR. Both the high uptake in PET and the abnormal findings in MR gave strong evidence for prostate cancer at the ventral periphery of the right apex. This location is sometimes not covered by routine sextant biopsy. The following targeted rebiopsy was positive for prostate cancer. This case indicates the potential role of PET/MR for identifying primary prostate cancer because of its high soft tissue contrast and the possibility of a multimodality approach.