4‐Hydroxylation of Isoxazolines; Synthesis of rac‐Phytosphingosine (ribo‐2‐Amino‐1,3,4‐octadecanetriol)

Wilfried Schwab, Volker Jäger

Research output: Contribution to journalArticlepeer-review

60 Scopus citations

Abstract

The shortest and most effective phytosphingosine synthesis so far was achieved after a concept, according to which various amine sugars can be easily “assembled”. The two decisive steps in the preparation of the title compound 3, which proceed highly stereoselectively, are the hydroxylation of the isoxazoline 1 and the LiAlH4‐reduction of 2. (Figure Presented.)

Original languageEnglish
Pages (from-to)603-605
Number of pages3
JournalAngewandte Chemie International Edition in English
Volume20
Issue number6-7
DOIs
StatePublished - 1981
Externally publishedYes

Fingerprint

Dive into the research topics of '4‐Hydroxylation of Isoxazolines; Synthesis of rac‐Phytosphingosine (ribo‐2‐Amino‐1,3,4‐octadecanetriol)'. Together they form a unique fingerprint.

Cite this